Understanding Unreported Cases in the COVID-19 Epidemic Outbreak in Wuhan, China, and the Importance of Major Public Health Interventions

Author:

Liu Zhihua,Magal Pierre,Seydi Ousmane,Webb Glenn

Abstract

We develop a mathematical model to provide epidemic predictions for the COVID-19 epidemic in Wuhan, China. We use reported case data up to 31 January 2020 from the Chinese Center for Disease Control and Prevention and the Wuhan Municipal Health Commission to parameterize the model. From the parameterized model, we identify the number of unreported cases. We then use the model to project the epidemic forward with varying levels of public health interventions. The model predictions emphasize the importance of major public health interventions in controlling COVID-19 epidemics.

Publisher

MDPI AG

Subject

General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology

Reference8 articles.

1. Chinese Center for Disease Control and Preventionhttp://www.chinacdc.cn/jkzt/crb/zl/szkb_11803/jszl_l11809/

2. New England Journal of Medicine, Letter to the Editorhttps://www.nejm.org/doi/full/10.1056/NEJMc2001468

3. Estimation of the Transmission Risk of the 2019-nCoV and Its Implication for Public Health Interventions

4. The parameter identification problem for SIR epidemic models: identifying unreported cases

5. Identifying the number of unreported cases in SIR epidemic models

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