Approaching Artificial Intelligence in Orthopaedics: Predictive Analytics and Machine Learning to Prognosticate Arthroscopic Rotator Cuff Surgical Outcomes

Author:

Potty Anish G.123ORCID,Potty Ajish S. R.1,Maffulli Nicola4567ORCID,Blumenschein Lucas A.8,Ganta Deepak9ORCID,Mistovich R. Justin8,Fuentes Mario9,Denard Patrick J.10ORCID,Sethi Paul M.11,Shah Anup A.12,Gupta Ashim1131415ORCID

Affiliation:

1. South Texas Orthopedic Research Institute (STORI Inc.), Laredo, TX 78045, USA

2. The Institute of Musculoskeletal Excellence (TIME Orthopaedics), Laredo, TX 78041, USA

3. School of Osteopathic Medicine, The University of the Incarnate Word, San Antonio, TX 78209, USA

4. Department of Musculoskeletal Disorders, School of Medicine and Surgery, University of Salerno, 84084 Fisciano, Italy

5. San Giovanni di Dio e Ruggi D’Aragona Hospital “Clinica Ortopedica” Department, Hospital of Salerno, 84124 Salerno, Italy

6. Centre for Sports and Exercise Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 4DG, UK

7. School of Pharmacy and Bioengineering, Keele University School of Medicine, Stoke on Trent ST5 5BG, UK

8. Department of Orthopaedics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA

9. School of Engineering, Texas A&M International University, Laredo, TX 78041, USA

10. Southern Oregon Orthopedics, Medford, OR 97504, USA

11. Orthopaedic & Neurosurgery Specialists, Greenwich, CT 06905, USA

12. Kelsey-Seybold Clinic, Houston, TX 77584, USA

13. Future Biologics, Lawrenceville, GA 30043, USA

14. BioIntegrate, Lawrenceville, GA 30043, USA

15. Regenerative Orthopaedics, Noida 201301, Uttar Pradesh, India

Abstract

Machine learning (ML) has not yet been used to identify factors predictive for post-operative functional outcomes following arthroscopic rotator cuff repair (ARCR). We propose a novel algorithm to predict ARCR outcomes using machine learning. This is a retrospective cohort study from a prospectively collected database. Data were collected from the Surgical Outcome System Global Registry (Arthrex, Naples, FL, USA). Pre-operative and 3-month, 6-month, and 12-month post-operative American Shoulder and Elbow Surgeons (ASES) scores were collected and used to develop a ML model. Pre-operative factors including demography, comorbidities, cuff tear, tissue quality, and fixation implants were fed to the ML model. The algorithm then produced an expected post-operative ASES score for each patient. The ML-produced scores were compared to actual scores using standard test-train machine learning principles. Overall, 631 patients who underwent shoulder arthroscopy from January 2011 to March 2020 met inclusion criteria for final analysis. A substantial number of the test dataset predictions using the XGBoost algorithm were within the minimal clinically important difference (MCID) and substantial clinical benefit (SCB) thresholds: 67% of the 12-month post-operative predictions were within MCID, while 84% were within SCB. Pre-operative ASES score, pre-operative pain score, body mass index (BMI), age, and tendon quality were the most important features in predicting patient recovery as identified using Shapley additive explanations (SHAP). In conclusion, the proposed novel machine learning algorithm can use pre-operative factors to predict post-operative ASES scores accurately. This can further supplement pre-operative counselling, planning, and resource allocation. Level of Evidence: III.

Publisher

MDPI AG

Subject

General Medicine

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3