Extraction and Purification of Catechins from Tea Leaves: An Overview of Methods, Advantages, and Disadvantages

Author:

Cioanca Oana1ORCID,Lungu Ionut-Iulian2,Mita-Baciu Ioana3,Robu Silvia4,Burlec Ana Flavia5,Hancianu Monica1,Crivoi Florina6

Affiliation:

1. Department of Pharmacognosy, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

2. Department of General and Inorganic Chemistry, Faculty of Pharmacy, “Grigore. T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

3. Department of Pharmacology, Faculty of Medicine, “Grigore T. Popa” University of Medicine and Pharmacy, 700115 Iasi, Romania

4. Department of Pharmacognosy, Faculty of Medicine and Pharmacy, “Dunarea de Jos” University, 35 Al. I. Cuza Street, 800216 Galati, Romania

5. Department of Drug Analysis, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania

6. Department of Pharmaceutical Physics, Faculty of Pharmacy, “Grigore T. Popa” University of Medicine and Pharmacy, 16 University Street, 700115 Iasi, Romania

Abstract

This review study explores the complex methods involved in the extraction and purification of polyphenols, specifically catechins, prominent compounds that are bioactive and found in plant-based extracts and foods like tea. This study also addresses the challenges that may arise from the complex chemical structure of catechins and their inherent variability across botanical sources. Despite these shortcomings and obstacles, catechins and catechin derivatives present significant potential, particularly in healthcare but also in the food industry. Their enhanced antioxidant properties have been exhaustively investigated and associated with countless health benefits, making them promising agents with numerous applications, most notably in healthcare against chronic diseases. Furthermore, catechins have numerous applications across various industries, including food and beverage, cosmetics, agriculture, and materials science. This review is a compilation of the most notable and recent research found in the literature and emphasizes the importance of continued research and innovation in catechin separation, extraction, and utilization, which hold promise for advancing human health and technological progress across multiple domains.

Publisher

MDPI AG

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