Efficient Synthesis of β-Aryl-γ-lactams and Their Resolution with (S)-Naproxen: Preparation of (R)- and (S)-Baclofen-Reference-Cited by-同舟云学术

Efficient Synthesis of β-Aryl-γ-lactams and Their Resolution with (S)-Naproxen: Preparation of (R)- and (S)-Baclofen

Published:2015-12-10 Issue:12 Volume:20 Page:22028-22043
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Montoya-Balbás Iris,Valentín-Guevara Berenice,López-Mendoza Estefanía,Linzaga-Elizalde Irma,Ordoñez Mario,Román-Bravo Perla

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

http://www.mdpi.com/1420-3049/20/12/19830/pdf

Reference48 articles.

1. Discovery of substituted lactams as novel dual orexin receptor antagonists. Synthesis, preliminary structure–activity relationship studies and efforts towards improved metabolic stability and pharmacokinetic properties. Part 1

2. Lactam and oxazolidinone derived potent 5-hydroxytryptamine 6 receptor antagonists

3. Method for the preparation of 4-aryl-3-pyrrolin-2-ones and their 5-bromo derivatives

4. Rolipram: A specific phosphodiesterase 4 inhibitor with potential antipsychotic activity

5. Broad spectrum neuroprotection profile of phosphodiesterase inhibitors as related to modulation of cell-cycle elements and caspase-3 activation;Chen;Neurosci. Lett.,2007

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In Silico Analysis: Anti-Inflammatory and α-Glucosidase Inhibitory Activity of New α-Methylene-γ-Lactams;Molecules;2024-04-25

2. Maleic Acid as a Co-Former for Pharmaceutically Active GABA Derivatives: Mechanochemistry or Solvent Crystallization?;Materials;2023-03-10

3. An expedient copper-catalysed asymmetric synthesis of γ-lactones and γ-lactams. Application to the synthesis of lucidulactone A;Organic & Biomolecular Chemistry;2023

4. 3-Component Approach to 1,5-Dihydro-2H-pyrrol-2-one Heterocycles;Organic Syntheses;2023

5. Synthesis, structure, and biological activity of 4-hetaryl-2-pyrrolidones containing a pyrazole ring;Chemistry of Heterocyclic Compounds;2022-11