Coordination Complexes Built from a Ditopic Triazole-Pyrazole Ligand with Antibacterial and Antifungal Performances-Reference-Cited by-同舟云学术

Coordination Complexes Built from a Ditopic Triazole-Pyrazole Ligand with Antibacterial and Antifungal Performances

Published:2023-09-25 Issue:19 Volume:28 Page:6801
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Draoui Youssef¹,Radi Smaail¹^ORCID,El Massaoudi Mohamed¹,Bahjou Yousra¹²,Ouahhoud Sabir³^ORCID,Mamri Samira³,Ferbinteanu Marilena⁴^ORCID,Benabbes Redouane³,Wolff Mariusz⁵^ORCID,Robeyns Koen²^ORCID,Garcia Yann²^ORCID

Affiliation:

1. LCAE, Department of Chemistry, Faculty of Science, University Mohamed I, P.O. Box 524, Oujda 60 000, Morocco

2. Institute of Condensed Matter and Nanosciences, Molecular Chemistry, Materials and Catalysis (IMCN/MOST), Université Catholique de Louvain, Place Louis Pasteur 1, 1348 Louvain-la-Neuve, Belgium

3. Laboratory of Biochemistry and Biotechnology, Department of Biology, Faculty of Science, University Mohamed I, P.O. Box 524, Oujda 60 000, Morocco

4. Inorganic Chemistry Department, Faculty of Chemistry, University of Bucharest, Panduri Road, No. 90, 050663 Bucharest, Romania

5. Institute of Chemical Catalysis, Faculty of Chemistry, Universität Wien, Währinger Straße 38-42, 1090 Wien, Austria

Abstract

Four mononuclear complexes (H3O){[NiL3](ClO4)3} (1), [CoL3](ClO4)2·2H2O (2), [CdL2Cl2] (3) and [CuL3](NO3)2 (4) have been prepared employing a newly synthesized 1,2,4-triazole ligand: 3-(3,5-dimethyl-1H-pyrazol-1-yl)-1H-1,2,4-triazole (L). The structures of the complexes, which crystallized in P63/m (1), P-1 (2), P1 (3), and P21/c (4), are reviewed within the context of the cooperative effect of the hydrogen bonding network and counter anions on the supramolecular formations. Moreover, within the framework of biological activity examination, these compounds showed favorable antibacterial performances compared to those of various species of bacteria, including both Gram-positive and Gram-negative strains. Significant antifungal inhibitory activity towards Fusarium oxysporum f. sp. albedinis fungi was recorded for 3 and 4 over the ligand L.

Funder

PPR2-MESRSFC-CNRST-P10 project

ACRYRED COST action CA21149

Fonds De La Recherche Scientifique—FNRS

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/28/19/6801/pdf

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