Ergot Alkaloids on Cereals and Seeds: Analytical Methods, Occurrence, and Future Perspectives

Author:

Silva Ângela1,Mateus Ana Rita Soares12ORCID,Barros Sílvia Cruz2,Silva Ana Sanches134ORCID

Affiliation:

1. University of Coimbra, Faculty of Pharmacy, Polo III, Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal

2. National Institute for Agricultural and Veterinary Research (INIAV), I.P., 4485-655 Vila do Conde, Portugal

3. Center for Study in Animal Science (CECA), ICETA, University of Oporto, 4501-401 Oporto, Portugal

4. Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), 1300-477 Lisbon, Portugal

Abstract

Ergot alkaloids are secondary metabolites resulting from fungi of the genus Claviceps that have proven to be highly toxic. These mycotoxins commonly infect cereal crops such as wheat, rye, barley, and oats. Due to the increase worldwide consumption of cereal and cereal-based products, the presence of ergot alkaloids in food presents a concern for human safety. For this reason, it is essential to develop several analytical methods that allow the detection of these toxic compounds. This review compiles and discusses the most relevant studies and methods used in the detection and quantification of ergot alkaloids. Moreover, the decontamination techniques are also addressed, with special attention to sorting, cleaning, frying, baking, peeling, and ammonization methods, as they are the only ones already applied to ergot alkaloids.

Funder

FCT/MCTES

FCT

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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