Caudiquinol: A Meroterpenoid with an Intact C20 Geranylgeranyl Chain Isolated from Garcinia caudiculata-Reference-Cited by-同舟云学术

Caudiquinol: A Meroterpenoid with an Intact C20 Geranylgeranyl Chain Isolated from Garcinia caudiculata

Published:2024-07-31 Issue:15 Volume:29 Page:3613
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Valmiki Maya¹,Teo Stephen Ping²^ORCID,de Resende Pedro Ernesto³^ORCID,Gibbons Simon⁴^ORCID,Ganesan A.¹^ORCID

Affiliation:

1. School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, UK

2. Forest Department Sarawak Headquarters, Medan Raya, Petra Jaya, Kuching 93050, Sarawak, Malaysia

3. The John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK

4. Natural and Medical Sciences Research Center, University of Nizwa, PC 616, Birkat Al-Mauz, Nizwa P.O. Box 33, Oman

Abstract

The tropical Garcinia genus of flowering plants is a prolific producer of aromatic natural products including polyphenols, flavonoids, and xanthones. In this study, we report the first phytochemical investigation of Garcinia caudiculata Ridl. from the island of Borneo. Fractionation, purification, and structure elucidation by MS and NMR resulted in the discovery of two meroterpenoids. One was a benzofuranone lactone previously isolated from Iryanthera grandis and Rhus chinensis, and the second was a new hydroquinone methyl ester that we named caudiquinol. Both natural products are rare examples of plant meroterpenoids with an intact geranylgeranyl chain.

Publisher

MDPI AG

Link

https://www.mdpi.com/1420-3049/29/15/3613/pdf

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