Research Progress on Extraction, Isolation, Structural Analysis and Biological Activity of Polysaccharides from Panax Genus

Author:

Zhang Shuai1,Ding Chuanbo2,Liu Xinglong2,Zhao Yingchun1,Ding Qiteng1,Sun Shuwen1,Zhang Jinping1,Yang Jiali1,Liu Wencong3,Li Wei14ORCID

Affiliation:

1. College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China

2. College of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China

3. School of Food and Pharmaceutical Engineering, Wuzhou University, Wuzhou 543003, China

4. College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun 130118, China

Abstract

The panax genus is a widely used medicinal plant with good biological activity. As one of the main active components of the Panax genus, polysaccharides have various pharmacological effects. This review summarizes the latest research reports on ginseng, American ginseng, and Panax notoginseng polysaccharides and compares the differences in extraction, isolation and purification, structural characteristics, and biological activities. The current research mainly focuses on ginseng polysaccharides, and the process of extraction, isolation, and structure analysis of each polysaccharide is roughly the same. Modern pharmacological studies have shown that these polysaccharides have antioxidants, antitumor, immunomodulatory, antidiabetic, intestinal protection, skin repair, and other biological activities. This review provides new insights into the differences between the three kinds of ginseng polysaccharides which will help to further study the medicinal value of ginseng in traditional Chinese medicine.

Funder

Natural Science Foundation of Jilin Province

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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