The Extraction, Determination, and Bioactivity of Curcumenol: A Comprehensive Review-Reference-Cited by-同舟云学术

The Extraction, Determination, and Bioactivity of Curcumenol: A Comprehensive Review

Published:2024-01-30 Issue:3 Volume:29 Page:656
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Li Jie¹²³,Sun Yitian¹²,Li Guohua¹²,Cheng Chunsong⁴^ORCID,Sui Xinbing²,Wu Qibiao¹⁵⁶^ORCID

Affiliation:

1. State Key Laboratory of Quality Research in Chinese Medicines, Faculty of Chinese Medicine, Macau University of Science and Technology, Macau 999078, China

2. College of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China

3. School of Environmental and Chemical Engineering, Zhaoqing University, Zhaoqing 526061, China

4. Lushan Botanical Garden, Chinese Academy of Sciences, Jiujiang 332900, China

5. Zhuhai M.U.S.T. Science and Technology Research Institute, Zhuhai 519031, China

6. Guangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Guangzhou 510006, China

Abstract

Curcuma wenyujin is a member of the Curcuma zedoaria (zedoary, Zingiberaceae) family, which has a long history in traditional Chinese medicine (TCM) due to its abundant biologically active constituents. Curcumenol, a component of Curcuma wenyujin, has several biological activities. At present, despite different pharmacological activities being reported, the clinical usage of curcumenol remains under investigation. To further determine the characteristics of curcumenol, the extraction, determination, and bioactivity of the compound are summarized in this review. Existing research has reported that curcumenol exerts different pharmacological effects in regard to a variety of diseases, including anti-inflammatory, anti-oxidant, anti-bactericidal, anti-diabetic, and anti-cancer activity, and also ameliorates osteoporosis. This review of curcumenol provides a theoretical basis for further research and clinical applications.

Funder

Science and Technology Development Fund, Macau SAR

Jiangxi Province Double Thousand Talents-Leader of Natural Science Talents Project

Macau University of Science and Technology’s Faculty Research Grant

Publisher

MDPI AG

Link

https://www.mdpi.com/1420-3049/29/3/656/pdf

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