Status of Omics Research Capacity on Oral Cancer in Africa: A Systematic Scoping Review Protocol

Author:

Nnyanzi Lawrence Achilles12ORCID,Adisa Akinyele Olumuyiwa3ORCID,Kanmodi Kehinde Kazeem145ORCID,Aladelusi Timothy Olukunle6ORCID,Salami Afeez Abolarinwa46ORCID,Amzat Jimoh78ORCID,Angione Claudio9ORCID,Nwafor Jacob Njideka410ORCID,Uwambaye Peace11ORCID,Okee Moses12,Kuba Shweta Yogesh1ORCID,Mujuni Brian12,Ibingira Charles12,Ogbureke Kalu Ugwa Emmanuel13ORCID,Jayasinghe Ruwan Duminda1415ORCID

Affiliation:

1. Head and Neck Cancer Working Group, School of Health and Life Sciences, Teesside University, Middlesbrough TS1 3BX, UK

2. School of Public Health, King Ceasar University, Kampala P.O. Box 88, Uganda

3. Department of Oral Pathology, University of Ibadan, Ibadan 200005, Nigeria

4. Campaign for Head and Neck Cancer Education (CHANCE) Programme, Cephas Health Research Initiative Inc., Ibadan 200005, Nigeria

5. Faculty of Dentistry, University of Puthisastra, Phnom Penh 120204, Cambodia

6. Department of Oral and Maxillofacial Surgery, University College Hospital/University of Ibadan, Ibadan 200005, Nigeria

7. Department of Sociology, Usmanu Danfodiyo University, Sokoto 84001, Nigeria

8. Department of Sociology, University of Johannesburg, Johannesburg 2001, South Africa

9. School of Computing, Engineering, and Digital Technologies, Teesside University, Middlesbrough TS1 3BX, UK

10. Division of Medicine, Nottingham University Teaching Hospital NHS Trust, Nottingham NG7 2GT, UK

11. Department of Preventive and Community Dentistry, University of Rwanda, Kigali 4285, Rwanda

12. College of Health Sciences, Makerere University, Kampala P.O. Box 88, Uganda

13. School of Dentistry, University of Texas Health Science Center at Houston, Houston, TX 77054, USA

14. Department of Oral Medicine and Periodontology, Faculty of Dental Sciences, University of Peradeniya, Peradeniya 20400, Sri Lanka

15. Center for Research in Oral Cancer, Faculty of Dental Sciences, University of Peradeniya, Peradeniya 20400, Sri Lanka

Abstract

Over the past decade, omics technologies such as genomics, epigenomics, transcriptomics, proteomics, and metabolomics have been used in the scientific understanding of diseases. While omics technologies have provided a useful tool for the diagnosis and treatment of diseases globally, there is a dearth of literature on the use of these technologies in Africa, particularly in the diagnosis and treatment of oral cancer. This systematic scoping review aims to present the status of the omics research capacity on oral cancer in Africa. The guidelines by the Joanna Brigg’s Institute for conducting systematic scoping reviews will be adopted for this review’s methodology and it will be reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) checklist. The literature that will be reviewed will be scooped out from PubMed, SCOPUS, Dentistry and Oral Sciences Source, AMED, CINAHL, and PsycInfo databases. In conclusion, the findings that will be obtained from this review will aid the in-depth understanding of the status of oral cancer omics research in Africa, as this knowledge is paramount for the enhancement of strategies required for capacity development and the prioritization of resources in the fight against oral cancer in Africa.

Publisher

MDPI AG

Subject

Management Science and Operations Research,Mechanical Engineering,Energy Engineering and Power Technology

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