IEUBK Modeling of Children’s Blood Lead Levels in Homes Served by Private Domestic Wells in Three Illinois Counties

Author:

Keeley Sarah1ORCID,Dorevitch Samuel23ORCID,Kelly Walton4,Jacobs David E.25ORCID,Geiger Sarah D.6

Affiliation:

1. Department of Occupational & Environmental Health Sciences, School of Public Health, West Virginia University, Morgantown, WV 26506, USA

2. Division of Environmental and Occupational Health Sciences, School of Public Health, University of Illinois Chicago, Chicago, IL 60612, USA

3. Institute for Environmental Science and Policy, University of Illinois Chicago, Chicago, IL 60612, USA

4. Illinois State Water Survey, Prairie Research Institute, University of Illinois Urbana-Champaign, Champaign, IL 61820, USA

5. National Center for Healthy Housing, Columbia, MD 21044, USA

6. Department of Kinesiology and Community Health, University of Illinois Urbana-Champaign, Champaign, IL 61820, USA

Abstract

Lead is known to impair neurocognitive development in children. Drinking water is routinely monitored for lead content in municipal systems, but private well owners are not required to test for lead. The lack of testing poses a risk of lead exposure and resulting health effects to rural children. In three Illinois counties, we conducted a cross-sectional study (n = 151 homes) examining water lead levels (WLLs), water consumption, and water treatment status to assess risk of lead exposure among residents using private water wells. Since blood lead levels (BLLs) were not available, EPA’s Integrated Exposure Uptake Biokinetic (IEUBK) modeling was used to estimate the incremental contribution of WLL to BLL, holding all other sources of lead at their default values. Nearly half (48.3%) of stagnant water samples contained measurable lead ranging from 0.79 to 76.2 µg/L (median= 0.537 µg/L). IEUBK modeling showed BLLs rose from 0.3 to 0.4 µg/dL when WLLs rose from 0.54 µg/L (the tenth percentile) to 4.88 µg/L (the 90th percentile). Based on IEUBK modeling, 18% of children with a WLL at the 10th percentile would have a BLL above 3.5 µg/dL compared to 27.4% of those with a WLL at the 90th percentile. These findings suggest that the consumption of unfiltered well water likely results in increased blood lead levels in children.

Funder

U.S Department of Housing and Urban Development

Publisher

MDPI AG

Reference44 articles.

1. Liu, J., Li, L., Wang, Y., Yan, C., and Liu, X. (2013). Impact of Low Blood Lead Concentrations on IQ and School Performance in Chinese Children. PLoS ONE, 8.

2. Blood Lead Concentrations and Children’s Behavioral and Emotional Problems: A Cohort Study;Liu;JAMA Pediatr.,2014

3. U.S. Department of Health and Human Services (2012). National Toxicology Program. NTP monograph on health effects of low-level lead. NTP Monogr., xiii, xv-148.

4. Neurobehavioral function in children with low blood lead concentrations;Min;Neurotoxicology,2007

5. Pb Neurotoxicity: Neuropsychological Effects of Lead Toxicity;Mason;BioMed Res. Int.,2014

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3