Is There a Future for Traditional Immunogens When We Have mRNA?

Author:

Kyuregyan Karen K.12ORCID,Jansons Juris34ORCID,Isaguliants Maria4ORCID

Affiliation:

1. Central Research Institute of Epidemiology, 111123 Moscow, Russia

2. Scientific and Educational Resource Center for High-Performance Methods of Genomic Analysis, Peoples’ Friendship University of Russia (RUDN University), 117198 Moscow, Russia

3. Latvian Biomedical Research and Study Centre, LV-1067 Riga, Latvia

4. Department of Research, Riga Stradins University, LV-1007 Riga, Latvia

Abstract

As the SARS-CoV-2 pandemic ends and we enter into a post-pandemic world, it is the time to reflect on the lessons learned [...]

Publisher

MDPI AG

Subject

Virology,Microbiology (medical),Microbiology

Reference8 articles.

1. Isaguliants, M., Krotova, O., Petkov, S., Jansons, J., Bayurova, E., Mezale, D., Fridrihsone, I., Kilpelainen, A., Podschwadt, P., and Agapkina, Y. (2021). Cellular Immune Response Induced by DNA Immunization of Mice with Drug Resistant Integrases of HIV-1 Clade A Offers Partial Protection against Growth and Metastatic Activity of Integrase-Expressing Adenocarcinoma Cells. Microorganisms, 9.

2. Jansons, J., Skrastina, D., Kurlanda, A., Petkov, S., Avdoshina, D., Kuzmenko, Y., Krotova, O., Trofimova, O., Gordeychuk, I., and Sominskaya, I. (2021). Reciprocal Inhibition of Immunogenic Performance in Mice of Two Potent DNA Immunogens Targeting HCV-Related Liver Cancer. Microorganisms, 9.

3. Msafiri, F., Joachim, A., Held, K., Nadai, Y., Chissumba, R.M., Geldmacher, C., Aboud, S., Stöhr, W., Viegas, E., and Kroidl, A. (2020). Frequent Anti-V1V2 Responses Induced by HIV-DNA Followed by HIV-MVA with or without CN54rgp140/GLA-AF in Healthy African Volunteers. Microorganisms, 8.

4. Tran, P.-T.-H., Asghar, N., Höglund, U., Larsson, O., Haag, L., Mirazimi, A., Johansson, M., and Melik, W. (2020). Development of a Multivalent Kunjin Virus Reporter Virus-Like Particle System Inducing Seroconversion for Ebola and West Nile Virus Proteins in Mice. Microorganisms, 8.

5. Tuchynskaya, K., Volok, V., Illarionova, V., Okhezin, E., Polienko, A., Belova, O., Rogova, A., Chernokhaeva, L., and Karganova, G. (2021). Experimental Assessment of Possible Factors Associated with Tick-Borne Encephalitis Vaccine Failure. Microorganisms, 9.

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