The Host–Pathogen Interplay: A Tale of Two Stories within the Cornea and Posterior Segment

Author:

Dempsey Michael P.1ORCID,Conrady Christopher D.12ORCID

Affiliation:

1. Department of Ophthalmology and Visual Sciences, Truhlsen Eye Center, University of Nebraska Medical Center, Omaha, NE 68105, USA

2. Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA

Abstract

Ocular infectious diseases are an important cause of potentially preventable vision loss and blindness. In the following manuscript, we will review ocular immunology and the pathogenesis of herpesviruses and Pseudomonas aeruginosa infections of the cornea and posterior segment. We will highlight areas of future research and what is currently known to promote bench-to-bedside discoveries to improve clinical outcomes of these debilitating ocular diseases.

Funder

Knights Templar Eye Foundation career starter grant

IDeA Clinical and Translational Research Early Career Investigator Program

University of Nebraska Medical Center

National Eye Institute for a K08 career development award

Publisher

MDPI AG

Subject

Virology,Microbiology (medical),Microbiology

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