The Acceptability of Pharmacy-Based HPV Vaccination in Western Kenya among Pharmacy Clients and Providers

Author:

Zhang Shengruo1ORCID,Kwach Benn2,Omollo Victor2,Asewe Magdaline2,Malen Rachel C.3,Shah Parth D.3ORCID,Odoyo Josephine2,Mugo Nelly45,Ngure Kenneth6ORCID,Bukusi Elizabeth A.257,Ortblad Katrina F.3

Affiliation:

1. Department of Epidemiology, University of Washington, Seattle, WA 98195, USA

2. Centre for Microbiology Research, Kenya Medical Research Institute, Nairobi 00200, Kenya

3. Public Health Sciences Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA

4. Center for Clinical Research, Kenya Medical Research Institute, Nairobi 00200, Kenya

5. Department of Global Health, University of Washington, Seattle, WA 98195, USA

6. School of Public Health, Jomo Kenyatta University of Agriculture and Technology, Nairobi 00200, Kenya

7. Department of Obstetrics and Gynecology, University of Washington, Seattle, WA 98195, USA

Abstract

Vaccine coverage for the human papillomavirus (HPV) remains low globally, and differentiated models of vaccine delivery are needed to expand access. Pharmacy-based models of the HPV vaccination may engage women who could benefit. We assessed the acceptability of such a model among pharmacy clients and providers at 20 private pharmacies in Kisumu County, Kenya. In questionnaires, participants (≥18 years) were asked the extent they agreed (5-point scale) with statements that assessed different acceptability component constructs outlined in the Theoretical Framework of Acceptability (TFA). From March to June 2022, 1500 pharmacy clients and 40 providers were enrolled and completed questionnaires. Most clients liked the intervention (TFA: affective attitude; 96%, 1435/1500) and did not think it would be hard to obtain (TFA: burden; 93%, 1399/1500). All providers agreed the intervention could reduce HPV infection (TFA: perceived effectiveness) and felt confident they could deliver it (TFA: self-efficacy). Among the clients who had received or were planning to receive the HPV vaccine in the future, half (50%, 178/358) preferred a pharmacy-based HPV vaccination. In this study, most Kenyan pharmacy clients and providers perceived a pharmacy-delivered HPV vaccination as highly acceptable; however, more research is needed to test the feasibility and effectiveness of this novel vaccine delivery model in Africa.

Funder

Bill and Melinda Gates Foundation

National Institute of Mental Health

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Drug Discovery,Pharmacology,Immunology

Reference39 articles.

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2. The burden of human papillomavirus infections and related diseases in sub-saharan Africa;Alemany;Vaccine,2013

3. Invasive cervical cancers in the United States, Botswana and Kenya: HPV type distribution and health policy implications;Ermel;Infect. Agents Cancer,2016

4. PATH (2020). Global HPV Vaccine Introduction Overview: Projected and Current National Introductions, Demonstration/Pilot Projects, Gender-Neutral Vaccination Programs, and Global HPV Vaccine Introduction Maps (2006–2023), PATH.

5. Reflection: Burden of cervical cancer in Sub-Saharan Africa and progress with HPV vaccination;Ngcobo;Curr. Opin. Immunol.,2021

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