COVID-19 Vaccines Status, Acceptance and Hesitancy among Maintenance Hemodialysis Patients: A Cross-Sectional Study and the Implications for Pakistan and Beyond

Author:

Amjad Zara1,Maryam Iqra2,Munir Maria3,Salman Muhammad4ORCID,Baraka Mohamed A.56ORCID,Mustafa Zia Ul78ORCID,Khan Yusra Habib9ORCID,Mallhi Tauqeer Hussain9ORCID,Hasan Syed Shahzad10ORCID,Meyer Johanna C.1112ORCID,Godman Brian111314ORCID

Affiliation:

1. Department of Paediatrics, District Head Quarter (DHQ), Bhakkar 30000, Pakistan

2. Department of Medicine, Jinnah Hospital Lahore, Lahore 54000, Pakistan

3. Department of Medicine, Faisalabad Medical University, Faisalabad 38000, Pakistan

4. Institute of Pharmacy, Faculty of Pharmaceutical and Allied Health Sciences, Lahore College for Women University, Lahore 54000, Pakistan

5. Clinical Pharmacy Program, College of Pharmacy, Al Ain Campus, Al Ain University, Abu Dhabi P.O. Box 64141, United Arab Emirates

6. Clinical Pharmacy Department, College of Pharmacy, Al-Azhar University, Cairo 11651, Egypt

7. Discipline of Clinical Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Gelugor 11800, Penang, Malaysia

8. Department of Pharmacy Services, District Headquarter (DHQ) Hospital, Pakpattan 57400, Pakistan

9. Department of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka 72388, Saudi Arabia

10. Department of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield HD1 3DH, UK

11. Department of Public Health Pharmacy and Management, School of Pharmacy, Sefako Makgatho Health Sciences University, Ga-Rankuwa 0208, South Africa

12. South African Vaccination and Immunisation Centre, Sefako Makgatho Health Sciences University, Molotlegi Street, Ga-Rankuwa 0208, South Africa

13. Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman P.O. Box 346, United Arab Emirates

14. Strathclyde Institute of Pharmacy and Biomedical Science (SIPBS), University of Strathclyde, Glasgow G4 0RE, UK

Abstract

COVID-19 vaccine hesitancy continues to be a widespread problem in Pakistan due to various conspiracy beliefs, myths and misconceptions. Since the hemodialysis population is at a higher risk of contracting infections, we sought to investigate the current COVID-19 immunization status and reasons for any vaccine hesitancy among these patients in Pakistan. This cross-sectional study was conducted among maintenance hemodialysis patients at six hospitals in the Punjab Province of Pakistan. Data were collected anonymously using a questionnaire. A total of 399 hemodialysis patients took part in the survey, the majority of them were male (56%) and aged 45–64 years. A calculated 62.4% of the patients reported receiving at least one dose of the COVID-19 vaccine. Of those vaccinated (249), 73.5% had received two doses and 16.9% had received a booster dose. The most common reasons for vaccination were “being aware they were at high risk” (89.6%), “fear of getting infected” (89.2%) and “willingness to fight against COVID-19-pandemic” (83.9%). Of the 150 patients who had not yet been vaccinated, only 10 showed a willingness to take the COVID-19 vaccine. The major reasons for refusal included “COVID-19 is not a real problem” (75%), the “corona vaccine is a conspiracy (72.1%)” and “I don’t need the vaccine” (60.7%). Our study revealed that only 62% patients receiving hemodialysis were partially or completely vaccinated against COVID-19. Consequently, there is a need to initiate aggressive approaches to educate this high-risk population in order to address their concerns with vaccine safety and efficacy as well as correct current myths and misconceptions to improve the COVID-19 immunization status in this population.

Publisher

MDPI AG

Subject

Pharmacology (medical),Infectious Diseases,Drug Discovery,Pharmacology,Immunology

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