1. Department of Dermatology, Cancer Center, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan
2. School of Medicine, National Cheng Kung University, Tainan 701, Taiwan
3. Department of Biochemistry and Molecular Biology, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan
4. Center of Applied Nanomedicine, National Cheng Kung University, Tainan 701, Taiwan