Abstract
In chronic non-cancer pain (CNCP), evidence of the effectiveness of strong opioids (SO) is very limited. Despite this, their use is increasingly common. To examine SO prescriptions, we designed a descriptive, longitudinal, retrospective population-based study, including patients aged ≥15 years prescribed SO for ≥3 months continuously in 2013–2017 for CNCP in primary care in Catalonia. Of the 22,691 patients included, 17,509 (77.2%) were women, 10,585 (46.6%) were aged >80 years, and most had incomes of <€18,000 per year. The most common diagnoses were musculoskeletal diseases and psychiatric disorders. There was a predominance of transdermal fentanyl in the defined daily dose (DDD) per thousand inhabitants/day, with the greatest increase for tapentadol (312% increase). There was an increase of 66.89% in total DDD per thousand inhabitants/day for SO between 2013 (0.737) and 2017 (1.230). The mean daily oral morphine equivalent dose/day dispensed for all drugs was 83.09 mg. Transdermal fentanyl and immediate transmucosal release were the largest cost components. In conclusion, there was a sustained increase in the prescription of SO for CNCP, at high doses, and in mainly elderly patients, predominantly low-income women. The new SO are displacing other drugs.
Funder
Spanish Society of Family and Community Medicine
Reference49 articles.
1. L’estat de Salut, Els Comportaments Relacionats Amb La Salut i l’ús de Serveis Sanitaris a Catalunya, 2020. Resum Executiu Dels Principals Resultats de l’ESCA Del 2020. Direcció General de Planificació En Salut. Generalitat de Catalunya;Medina,2021
2. La Atención Al Paciente Con Dolor Crónico No Oncológico (DCNO) En Atención Primaria (AP),2017
3. Complexity, comorbidity, and health care costs associated with chronic widespread pain in primary care
4. Consens Català de Dolor Crònic No Oncològic. Camfic, Societat Catalana Del Dolor;Batet,2017
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