Investigating the Effects of a Focal Muscle Vibration Protocol on Sensorimotor Integration in Healthy Subjects

Author:

Manzo Nicoletta1,Ginatempo Francesca2,Belvisi Daniele34,Arcara Giorgio1,Parrotta Ilaria15,Leodori Giorgio34ORCID,Deriu Franca26ORCID,Celletti Claudia7ORCID,Camerota Filippo7,Conte Antonella34ORCID

Affiliation:

1. IRCCS San Camillo Hospital, Via Alberoni 70, 30126 Venice, Italy

2. Department of Biomedical Sciences, University of Sassari, Viale San Pietro 43c, 07100 Sassari, Italy

3. Department of Human Neurosciences, Sapienza University of Rome, Viale dell’Università 30, 00185 Rome, Italy

4. IRCCS Neuromed, Via Atinense 18, 86077 Pozzilli, Italy

5. Movement Contral and Neuroplasticity Research Group, Tervuursevest 101, 3001 Leuven, Belgium

6. Unit of Endocrinology, Nutritional and Metabolic Disorders, AOU Sassari, 07100 Sassari, Italy

7. Physical Medicine and Rehabilitation Division, Umberto I University Hospital of Rome, 00185 Rome, Italy

Abstract

Background: The ability to perceive two tactile stimuli as asynchronous can be measured using the somatosensory temporal discrimination threshold (STDT). In healthy humans, the execution of a voluntary movement determines an increase in STDT values, while the integration of STDT and movement execution is abnormal in patients with basal ganglia disorders. Sensorimotor integration can be modulated using focal muscle vibration (fMV), a neurophysiological approach that selectively activates proprioceptive afferents from the vibrated muscle. Method: In this study, we investigated whether fMV was able to modulate STDT or STDT–movement integration in healthy subjects by measuring them before, during and after fMV applied over the first dorsalis interosseous, abductor pollicis brevis and flexor radialis carpi muscles. Results: The results showed that fMV modulated STDT–movement integration only when applied over the first dorsalis interosseous, namely, the muscle performing the motor task involved in STDT–movement integration. These changes occurred during and up to 10 min after fMV. Differently, fMV did not influence STDT at rest. We suggest that that fMV interferes with the STDT–movement task processing, possibly disrupting the physiological processing of sensory information. Conclusions: This study showed that FMV is able to modulate STDT–movement integration when applied over the muscle involved in the motor task. This result provides further information on the mechanisms underlying fMV, and has potential future implications in basal ganglia disorders characterized by altered sensorimotor integration.

Publisher

MDPI AG

Subject

General Neuroscience

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3