Affiliation:
1. Division of Pulmonary and Critical Care Medicine, Albany Medical College, Albany, NY 12208, USA
Abstract
The aim of this manuscript is to provide a comprehensive review of the etiology, measurement, and treatment of common pulmonary symptoms associated with sarcoidosis. The assessment of symptoms associated with pulmonary sarcoidosis is an important component of disease management. Some symptoms of pulmonary sarcoidosis are sensitive but nonspecific markers of disease activity, and the absence of such symptoms provides evidence that the disease is quiescent. Although quantifiable objective measurements of pulmonary physiology and chest imaging are important in the assessment of pulmonary sarcoidosis, they correlate poorly with the patient’s quality of life. Because the symptoms of pulmonary sarcoidosis directly relate to how the patient feels, they are reasonable endpoints in terms of clinical research and individual patient care. Recently, the symptoms of pulmonary sarcoidosis are capable of being quantified via patient-reported outcome measures and electronic devices. We conclude that a thorough assessment of the symptoms associated with pulmonary sarcoidosis improves patient care because it is a useful screen for manifestations of the disease, provides insight into the pathophysiology of manifestations of sarcoidosis, and may assist in optimizing treatment.
Reference98 articles.
1. Clinical characteristics of patients in a case control study of sarcoidosis;Baughman;Am. J. Respir. Crit. Care Med.,2001
2. The clinical course of sarcoidosis: Presentation, diagnosis, and treatment in a large white and black cohort in the United States;Judson;Sarcoidosis Vasc. Diffus. Lung Dis.,2012
3. Polverino, F., Balestro, E., and Spagnolo, P. (2020). Clinical Presentations, Pathogenesis, and Therapy of Sarcoidosis: State of the Art. J. Clin. Med., 9.
4. Endpoints for clinical trials of sarcoidosis;Baughman;Sarcoidosis Vasc. Diffus. Lung Dis.,2012
5. Biomarkers in sarcoidosis;Chopra;Expert. Rev. Clin. Immunol.,2016
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