Primary Varicella Infection in a Young Adult from the Democratic Republic of the Congo: A Case Report and Mini-Review

Author:

McNaughton Andrew1,Karsenti Nessika2ORCID,Kwan Jason3,Adawi Asal4,Mansuri Saniya5,Boggild Andrea K.467

Affiliation:

1. Department of Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada

2. Department of Medicine, Memorial University, Saint John’s, NF A1B 3V6, Canada

3. Department of Medicine, University of British Columbia, Vancouver, BC V1Y 1T3, Canada

4. Tropical Disease Unit, Toronto General Hospital, Toronto, ON M5G 2C4, Canada

5. TMC Innovation, Texas Medical Center, Houston, TX 77030, USA

6. Department of Medicine, University of Toronto, Toronto, ON M5S 1A1, Canada

7. Institute of Medical Science, University of Toronto, Toronto, ON M5S 1A8, Canada

Abstract

We describe a case of an immunocompetent adult male patient originally from the Democratic Republic of Congo (DRC), who was referred to our unit for a several-day history of fever and a pruritic, vesicular rash. There was initial concern in the Emergency Department for Mpox (formerly known as “monkeypox”) given the current epidemiology versus other viral etiologies. Primary varicella zoster virus (pVZV) infection was ultimately diagnosed by PCR from a swabbed, unroofed lesion, and he recovered completely with supportive management and without antiviral therapy. We herein describe how common viral exanthems may best be differentiated in an emergency or outpatient setting.

Funder

Departments of Medicine at the University of Toronto

University Health Network

Publisher

MDPI AG

Reference40 articles.

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2. Ministry of Health and Long-Term Care (2024, July 15). Two-Dose Varicella Immunization Schedule; Questions and Answers for Health Care Providers, Available online: https://www.health.gov.on.ca/en/public/programs/immunization/docs/qa_2dose.pdf.

3. Public Health Agency of Canada (2023, November 13). Varicella (Chickenpox) Vaccines: Canadian Immunization Guide, Available online: https://www.canada.ca/en/public-health/services/publications/healthy-living/canadian-immunization-guide-part-4-active-vaccines/page-24-varicella-chickenpox-vaccine.html.

4. A Tale of Two Viruses: Coinfections of Monkeypox and Varicella Zoster Virus in the Democratic Republic of Congo;Hughes;Am. J. Trop. Med. Hyg.,2021

5. (2023, November 13). Treatment of Varicella (Chickenpox) Infection—UpToDate. Available online: https://www.uptodate.com/contents/treatment-of-varicella-chickenpox-infection.

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