Impact of Age on Long-Term Urinary Continence after Robotic-Assisted Radical Prostatectomy

Author:

Cano Garcia Cristina12ORCID,Wenzel Mike1ORCID,Humke Clara1,Wittler Clarissa1,Dislich Julius1,Incesu Reha-Baris23,Köllermann Jens4ORCID,Steuber Thomas3,Graefen Markus3,Tilki Derya356ORCID,Karakiewicz Pierre I.2,Kluth Luis A.1,Preisser Felix1,Chun Felix K. H.1,Mandel Philipp1,Hoeh Benedikt1

Affiliation:

1. Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt, 60590 Frankfurt am Main, Germany

2. Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, QC H2X 0A9, Canada

3. Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, 20251 Hamburg, Germany

4. Dr. Senckenberg Institute of Pathology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany

5. Department of Urology, University Hospital Hamburg-Eppendorf, 20246 Hamburg, Germany

6. Department of Urology, Koc University Hospital, 34010 Istanbul, Turkey

Abstract

Aim and Objectives: We aimed to test the impact of age on long-term urinary continence (≥12 months) in patients undergoing robotic-assisted radical prostatectomy. Methods and Materials: We relied on an institutional tertiary-care database to identify the patients who underwent robotic-assisted radical prostatectomy between January 2014 and January 2021. Patients were divided into three age groups: age group one (≤60 years), age group two (61–69 years) and age group three (≥70 years). Multivariable logistic regression models tested the differences between the age groups in the analyses addressing long-term urinary continence after robotic-assisted radical prostatectomy. Results: Of the 201 prostate cancer patients treated with robotic-assisted radical prostatectomy, 49 (24%) were assigned to age group one (≤60 years), 93 (46%) to age group two (61–69 years) and 59 (29%) to age group three (≥70 years). The three age groups differed according to long-term urinary continence: 90% vs. 84% vs. 69% for, respectively, age group one vs. two vs. three (p = 0.018). In the multivariable logistic regression, age group one (Odds Ratio (OR) 4.73, 95% CI 1.44–18.65, p = 0.015) and 2 (OR 2.94; 95% CI 1.23–7.29; p = 0.017) were independent predictors for urinary continence, compared to age group three. Conclusion: Younger age, especially ≤60 years, was associated with better urinary continence after robotic-assisted radical prostatectomy. This observation is important at the point of patient education and should be discussed in informed consent.

Publisher

MDPI AG

Subject

General Medicine

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