Impact of Self-Reported Loss of Balance and Gait Disturbance on Outcomes following Adult Spinal Deformity Surgery

Author:

Diebo Bassel G.1,Alsoof Daniel1,Lafage Renaud2,Daher Mohammad1ORCID,Balmaceno-Criss Mariah1ORCID,Passias Peter G.3ORCID,Ames Christopher P.4,Shaffrey Christopher I.5ORCID,Burton Douglas C.6,Deviren Vedat4,Line Breton G.7,Soroceanu Alex8,Hamilton David Kojo9,Klineberg Eric O.10,Mundis Gregory M.11ORCID,Kim Han Jo12,Gum Jeffrey L.13ORCID,Smith Justin S.14,Uribe Juan S.15,Kebaish Khaled M.16,Gupta Munish C.17ORCID,Nunley Pierce D.18,Eastlack Robert K.11,Hostin Richard19,Protopsaltis Themistocles S.3,Lenke Lawrence G.20,Hart Robert A.21,Schwab Frank J.2,Bess Shay7ORCID,Lafage Virginie2,Daniels Alan H.1

Affiliation:

1. Department of Orthopedics, Warren Alpert Medical School of Brown University, East Providence, RI 02914, USA

2. Department of Orthopedic Surgery, Lenox Hill Northwell, New York, NY 10075, USA

3. Department of Orthopedics, NYU Langone Orthopedic Hospital, New York, NY 10016, USA

4. Department of Neurosurgery, University of California, San Francisco, CA 94115, USA

5. Department of Neurosurgery, Duke Spine Division, Durham, NC 27708, USA

6. Department of Orthopaedic Surgery, University of Kansas Medical Center, 3901 Rainbow Blvd., Kansas City, KS 66160, USA

7. Denver International Spine Center, Denver, CO 80218, USA

8. Department of Orthopedic Surgery, University of Calgary, Calgary, AB T2N 1N4, Canada

9. Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15260, USA

10. Department of Orthopaedic Surgery, University of California, 1 Shields Ave., Davis, CA 95616, USA

11. San Diego Spine, La Jolla, CA 92037, USA

12. Hospital for Special Surgery, New York, NY 10021, USA

13. Leatherman Spine Center, Louisville, KY 40202, USA

14. Department of Neurosurgery, University of Virginia, Charlottesville, VA 22903, USA

15. Department of Neurosurgery, Barrow Neurological Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ 85013, USA

16. Johns Hopkins University School of Medicine, Baltimore, MD 21218, USA

17. Department of Orthopedics, Washington University in St Louis, St. Louis, MO 63110, USA

18. Spine Institute of Louisiana, Shreveport, LA 71101, USA

19. Department of Orthopaedic Surgery, Baylor Scoliosis Center, 4708 Alliance Blvd #800, Plano, TX 75093, USA

20. Department of Orthopedic Surgery, Columbia University Medical Center, The Spine Hospital at New York Presbyterian, New York, NY 10032, USA

21. Swedish Neuroscience Institute, Seattle, WA 98027, USA

Abstract

Background: The objective of this study was to evaluate if imbalance influences complication rates, radiological outcomes, and patient-reported outcomes (PROMs) following adult spinal deformity (ASD) surgery. Methods: ASD patients with baseline and 2-year radiographic and PROMs were included. Patients were grouped according to whether they answered yes or no to a recent history of pre-operative loss of balance. The groups were propensity-matched by age, pelvic incidence–lumbar lordosis (PI-LL), and surgical invasiveness score. Results: In total, 212 patients were examined (106 in each group). Patients with gait imbalance had worse baseline PROM measures, including Oswestry disability index (45.2 vs. 36.6), SF-36 mental component score (44 vs. 51.8), and SF-36 physical component score (p < 0.001 for all). After 2 years, patients with gait imbalance had less pelvic tilt correction (−1.2 vs. −3.6°, p = 0.039) for a comparable PI-LL correction (−11.9 vs. −15.1°, p = 0.144). Gait imbalance patients had higher rates of radiographic proximal junctional kyphosis (PJK) (26.4% vs. 14.2%) and implant-related complications (47.2% vs. 34.0%). After controlling for age, baseline sagittal parameters, PI-LL correction, and comorbidities, patients with imbalance had 2.2-times-increased odds of PJK after 2 years. Conclusions: Patients with a self-reported loss of balance/unsteady gait have significantly worse PROMs and higher risk of PJK.

Funder

DePuy Syntheses Spine, NuVasive, K2/Stryker

Publisher

MDPI AG

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