Affiliation:
1. Centre for Genetic Improvement of Livestock, Department of Animal Biosciences, University of Guelph, 50 Stone Rd E, Guelph, ON N1G 2W1, Canada
Abstract
Gastrointestinal nematodes (GINs) are a major problem affecting sheep production systems worldwide. The flocks infected with GINs can undergo significant economic losses due to a decrease in productivity, the animals’ deaths, and the costs associated with treatments. The over-reliance on anthelmintics in the past years to eliminate GINs has resulted in the development of resistance against the available commercial anthelmintics. Genetically resistant animals can be used in mating systems to improve the overall flock resistance. This review aimed to summarize the estimated genetic parameters for resistance traits and genetic gains through the use of genetic/genomic selection for resistance to GINs in sheep. Heritability estimates from the literature ranged from 0.00 to 0.46 for fecal egg counts, 0.12 to 0.37 for packed cell volume/hematocrit, 0.07 to 0.26 for FAffa MAlan CHArt (FAMACHA©), from 0.10 to 0.37 for blood parameters, and 0.19 for Immunoglobulin A. Genetic correlations between traits measuring resistance to GINs and production traits ranged from negative to positive values in the literature. Genetic gains are possible when genetic/genomic selection for GIN resistance is applied. Therefore, genetic/genomic selection can be used to improve flocks’ resistance to GINs as a sustainable approach in sheep production systems.
Funder
Ontario Ministry of Agriculture, Food, and Rural Affairs
Ontario Agri-Food Innovation Alliance
Canada First Research Excellence Fund
Reference52 articles.
1. Genetic Parameters for Resistance to Gastrointestinal Nematodes in Sheep: A Meta-Analysis;Hayward;Int. J. Parasitol.,2022
2. Response to Teladorsagia Circumcincta Infection in Scottish Blackface Lambs with Divergent Phenotypes for Nematode Resistance;McRae;Vet. Parasitol.,2014
3. Miller, J.E., Kaplan, R.M., and Pugh, D.G. (2012). Sheep and Goat Medicine, Elsevier.
4. Identifying Hepatic Genes Regulating the Ovine Response to Gastrointestinal Nematodes Using RNA-Sequencing;Dixon;Front. Genet.,2023
5. Genetic Parameters for Resistance to Trichostrongylid Infection in Dairy Sheep;Meana;Animal,2010
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