Potential Anti-Tumorigenic Properties of Diverse Medicinal Plants against the Majority of Common Types of Cancer

Author:

Albahri Ghosoon1ORCID,Badran Adnan2,Abdel Baki Zaher3ORCID,Alame Mohamad1,Hijazi Akram1ORCID,Daou Anis4ORCID,Baydoun Elias5

Affiliation:

1. Plateforme de Recherche et d’Analyse en Sciences de l’Environnement (EDST-PRASE), Beirut P.O. Box 657314, Lebanon

2. Department of Nutrition, University of Petra Amman Jordan, Amman P.O. Box 961343, Jordan

3. College of Engineering and Technology, American University of the Middle East, Egaila 54200, Kuwait

4. Pharmaceutical Sciences Department, College of Pharmacy, QU Health, Qatar University, Doha P.O. Box 2713, Qatar

5. Department of Biology, American University of Beirut, Beirut 1107, Lebanon

Abstract

Globally, cancer is one of the primary causes of both morbidity and mortality. To prevent cancer from getting worse, more targeted and efficient treatment plans must be developed immediately. Recent research has demonstrated the benefits of natural products for several illnesses, and these products have played a significant role in the development of novel treatments whose bioactive components serve as both chemotherapeutic and chemo-preventive agents. Phytochemicals are naturally occurring molecules obtained from plants that have potential applications in both cancer therapy and the development of new medications. These phytochemicals function by regulating the molecular pathways connected to the onset and progression of cancer. Among the specific methods are immune system control, inducing cell cycle arrest and apoptosis, preventing proliferation, raising antioxidant status, and inactivating carcinogens. A thorough literature review was conducted using Google Scholar, PubMed, Scopus, Google Patent, Patent Scope, and US Patent to obtain the data. To provide an overview of the anticancer effects of several medicinal plants, including Annona muricata, Arctium lappa, Arum palaestinum, Cannabis sativa, Catharanthus roseus, Curcuma longa, Glycyrrhiza glabra, Hibiscus, Kalanchoe blossfeldiana, Moringa oleifera, Nerium oleander, Silybum marianum, Taraxacum officinale, Urtica dioica, Withania somnifera L., their availability, classification, active components, pharmacological activities, signaling mechanisms, and potential side effects against the most common cancer types were explored.

Publisher

MDPI AG

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