Maxillary Hypoplasia and Non-Invasive Ventilation: Literature Review and Proposed New Treatment Protocol

Author:

Meazzini Maria Costanza1,Moretti Mattia23,Canzi Gabriele4ORCID,Sozzi Davide25ORCID,Novelli Giorgio25ORCID,Mazzoleni Fabio12

Affiliation:

1. Pediatric Craniofacial Malformations Unit, Smile House Monza—Craniofacial Center, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy

2. Operative Unit of Maxillo-Facial Surgery, Fondazione IRCCS San Gerardo dei Tintori, 20900 Monza, Italy

3. Postgraduate School of Maxillo-Facial Surgery, University of Milan, 20122 Milan, Italy

4. Maxillo-Facial Surgery Unit, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milan, Italy

5. Department of Medicine and Surgery, School of Medicine and Surgery, University of Milan-Bicocca, 20900 Monza, Italy

Abstract

The impact of non-invasive ventilation (NIV) on pediatric maxillary growth is a subject of ongoing research considering its increased use in the pediatric population due to technological advancements and broader indications. This review examines the existing literature, encompassing original articles, case reports, and reviews, to evaluate the effects of NIV on maxillary development and explore potential treatment options. Although the majority of studies agree on the adverse effects of prolonged NIV on maxillary development, techniques for its correction remain understudied. Introducing a novel treatment protocol, we addressed the challenge of correcting severe midfacial hypoplasia in a child with congenital central hypoventilation syndrome (CCHS) undergoing NIV therapy, thus sidestepping the necessity for osteotomies. This proposed protocol holds promise in correcting the adverse impact of NIV on maxillary growth, emphasizing the need for further exploration into innovative treatment modalities.

Publisher

MDPI AG

Reference27 articles.

1. (2024, May 26). Medical Subject Headings (MeSH), Available online: https://www.ncbi.nlm.nih.gov/mesh/?term=Non+invasive+ventilation.

2. Gong, Y., and Sankari, A. (2022). Noninvasive Ventilation. StatPearls, StatPearls Publishing.

3. Noninvasive ventilation in children;Norregaard;Eur. Respir. J.,2002

4. Potchileev, I., Doroshenko, M., and Mohammed, A.N. (2023). Positive Pressure Ventilation. StatPearls, StatPearls Publishing.

5. Long-term non-invasive ventilation therapies in children: A scoping review;Dehaan;Sleep Med. Rev.,2018

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