An Acridine-Based Fluorescent Sensor for Monitoring ClO− in Water Samples and Zebrafish

Author:

Lee Su Chan,Park Soyoung,So Haeri,Lee Gyudong,Kim Ki-Tae,Kim Cheal

Abstract

A novel acridine-based fluorescent chemosensor, BK ((E)-2-((acridine-9-ylimino)methyl)-N-benzhydrylhydrazine-1-carbothioamide), for monitoring ClO− was prepared. The sensor BK was synthesized by introducing a new synthetic route of making aldehyde group using formic hydrazide. Probe BK displayed notable fluorescence quenching in the presence of ClO− and showed a great selectivity over other guest analytes. The detection limit was calculated to be 7.65 μM. Additionally, BK was satisfactorily applied for sensing ClO− in water samples and zebrafish.

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry

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