Ceramic Materials for Biomedical Applications: An Overview on Properties and Fabrication Processes

Author:

Vaiani Lorenzo1ORCID,Boccaccio Antonio1ORCID,Uva Antonio Emmanuele1ORCID,Palumbo Gianfranco1ORCID,Piccininni Antonio1ORCID,Guglielmi Pasquale1ORCID,Cantore Stefania2ORCID,Santacroce Luigi3ORCID,Charitos Ioannis Alexandros4ORCID,Ballini Andrea15ORCID

Affiliation:

1. Department of Mechanics, Mathematics and Management, Polytechnic University of Bari, Via Orabona 4, 70125 Bari, Italy

2. Independent Researcher, Sorriso & Benessere-Ricerca e Clinica, 70129 Bari, Italy

3. Microbiology and Virology Unit, Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, 70126 Bari, Italy

4. Emergency/Urgency Department, National Poisoning Center, Riuniti University Hospital of Foggia, 71122 Foggia, Italy

5. Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy

Abstract

A growing interest in creating advanced biomaterials with specific physical and chemical properties is currently being observed. These high-standard materials must be capable to integrate into biological environments such as the oral cavity or other anatomical regions in the human body. Given these requirements, ceramic biomaterials offer a feasible solution in terms of mechanical strength, biological functionality, and biocompatibility. In this review, the fundamental physical, chemical, and mechanical properties of the main ceramic biomaterials and ceramic nanocomposites are drawn, along with some primary related applications in biomedical fields, such as orthopedics, dentistry, and regenerative medicine. Furthermore, an in-depth focus on bone-tissue engineering and biomimetic ceramic scaffold design and fabrication is presented.

Funder

Italian Ministry of Education, University and Research

Fondo Sociale Europeo

Publisher

MDPI AG

Subject

Biomedical Engineering,Biomaterials

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