Abstract
We aimed to clarify the effectiveness of interventions in outpatients who did not undergo colorectal cancer (CRC) screening. From September 2012 to August 2013, we conducted a project, which showed that the immunological fecal occult blood test (FOBT) was actively recommended for outpatients who were ≥40 years of age, attended the Marumori Hospital regularly, and were not screened for CRC in the previous two years. We evaluated the detection rate of CRC and the disease specific survival ratio in February 2021 among patients with positive FOBT results during the retrospective cohort study. Overall, 388 (91%) out of the 425 outpatients submitted their stool samples. Among 388 outpatients, 66 tested positive for FOBT. While both the positive rate of FOBT and the detection rate of CRC (17% and 0.77%, respectively) were significantly higher than those in the nationwide administrative examination (5.7% and 0.13%, respectively) (p < 0.05), there was no statistically significant difference in the detection rate, compared with the group aged 65 years and older in the nationwide administrative examination. The 7-year CRC-specific survival ratio was 98.5%. Active promotion of FOBT at primary care institutions for outpatients who did not undergo CRC screening may contribute to reducing the frequency of CRC-related deaths.
Funder
Scientific Research from the Public Interest Incorporated Foundation for Development of the Community
Reference21 articles.
1. 2019 National Cancer Registry Report on Numbers and Rates of Patients with Cancer;Ministry of Health, Labour and Welfare of Japan,2019
2. 2020 Vital Statistics Summary: Table 6: Deaths by Sex in Terms of Simple Classifications of Causes of Death;Ministry of Health, Labour and Welfare of Japan,2021
3. The IARC Perspective on Colorectal Cancer Screening
4. Impact on colorectal cancer mortality of screening programmes based on the faecal immunochemical test
5. Screening for Colorectal Cancer: A Systematic Review and Meta-Analysis