Borderline Ventricles: From Evaluation to Treatment

Author:

Mazza Giuseppe Antonio1,Oreto Lilia2ORCID,Tuo Giulia3,Sirico Domenico4ORCID,Moscatelli Sara56ORCID,Meliota Giovanni7ORCID,Micari Antonio8,Guccione Paolo9,Rinelli Gabriele10,Favilli Silvia11

Affiliation:

1. Division of Pediatric Cardiology, City of Health and Science University Hospital, 10126 Turin, Italy

2. Department of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy

3. Pediatric Cardiology and Cardiac Surgery Unit, Surgery Department, IRCSS Istituto Giannina Gaslini, 16147 Genoa, Italy

4. Pediatric Cardiology Unit, Department of Women’s and Children’s Health, University of Padua, 35128 Padua, Italy

5. Centre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital, London WC1N 3JH, UK

6. Instutute of Cardiovascular Sciences, University College London, London WC1E 6DD, UK

7. Pediatric Cardiology, Giovanni XXIII Pediatric Hospital, 70126 Bari, Italy

8. Department of Biomedical, Dental Sciences and Morphological and Functional Images, Interventional Cardiology, University of Messina, 98122 Messina, Italy

9. Mediterranean Pediatric Cardiology Center, Bambino Gesù Children Hospital, 98039 Taormina, Italy

10. Pediatric Cardiology and Cardiac Arrhythmias and Syncope Unit, Bambino Gesù Children’s Hospital, 00146 Rome, Italy

11. Department of Pediatric Cardiology, Meyer Hospital, 50139 Florence, Italy

Abstract

A heart with a borderline ventricle refers to a situation where there is uncertainty about whether the left or right underdeveloped ventricle can effectively support the systemic or pulmonary circulation with appropriate filling pressures and sufficient physiological reserve. Pediatric cardiologists often deal with congenital heart diseases (CHDs) associated with various degrees of hypoplasia of the left or right ventricles. To date, no specific guidelines exist, and surgical management may be extremely variable in different centers and sometimes even in the same center at different times. Thus, the choice between the single-ventricle or biventricular approach is always controversial. The aim of this review is to better define when “small is too small and large is large enough” in order to help clinicians make the decision that could potentially affect the patient’s entire life.

Funder

Italian Society of Pediatric Cardiology

Publisher

MDPI AG

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