Subepidermal Low-Echogenic Band—Its Utility in Clinical Practice: A Systematic Review

Author:

Nicolescu Alin Codrut1ORCID,Ionescu Sinziana23ORCID,Ancuta Ioan24ORCID,Popa Valentin-Tudor5ORCID,Lupu Mihai6ORCID,Soare Cristina27ORCID,Cozma Elena-Codruta78,Voiculescu Vlad-Mihai27

Affiliation:

1. “Agrippa Ionescu” Emergency Clinical Hospital, 011773 Bucharest, Romania

2. Surgery Department, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania

3. Surgery Department, “Prof. Dr. Al. Trestioreanu” Oncology Institute Bucharest, 022328 Bucharest, Romania

4. Rheumatology Department, “Dr. I. Cantacuzino” Clinical Hospital, 020475 Bucharest, Romania

5. Dermatology Department, Center for Morphologic Study of the Skin MORPHODERM, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania

6. Department of Dermatology, MEDAS Medical Center, 030447 Bucharest, Romania

7. Dermatology Department, Elias University Emergency Hospital, 011461 Bucharest, Romania

8. Pathophysiology Department, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

Abstract

High-frequency ultrasonography (HF-USG) is a relatively new imaging method that allows the evaluation in a non-invasive manner of the skin layers and skin appendages. It is a diagnostic tool with increasing usefulness in numerous dermatological pathologies. High reproducibility, non-invasiveness and short diagnostic time make this method an increasingly used tool in dermatological practice. The subepidermal low-echogenic band is a relatively newly described parameter that seems to be a marker not only of intrinsic and extrinsic skin aging, but also of inflammatory processes taking place at the skin level. This systematic review aims to evaluate the role that SLEB has in the diagnosis and monitoring of the treatment of some inflammatory and non-inflammatory dermatological conditions, as well as its utility as a disease marker.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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