The Role of the Evans Index and the Maximal Width of the Frontal Horns of the Lateral Ventricles in the Diagnostic Imaging of Progressive Supranuclear Palsy and Multiple-System Atrophy

Author:

Kutyłowski Michał1,Alster Piotr2ORCID,Madetko-Alster Natalia2ORCID,Migda Anna Marta3,Królicki Leszek45,Migda Bartosz6ORCID

Affiliation:

1. Department of Radiology, Mazovian Brodnowski Hospital, 03-242 Warsaw, Poland

2. Department of Neurology, Medical University of Warsaw, 03-242 Warsaw, Poland

3. Department of Internal Medicine and Endocrinology, Medical University of Warsaw, 03-242 Warsaw, Poland

4. Department of Nuclear Medicine, Mazovian Brodnowski Hospital, 03-242 Warsaw, Poland

5. Department of Nuclear Medicine, Medical University of Warsaw, 02-097 Warsaw, Poland

6. Diagnostic Ultrasound Lab., Department of Pediatric Radiology, Medical Faculty, Medical University of Warsaw, 03-242 Warsaw, Poland

Abstract

Progressive Supranuclear Palsy and Multiple-System Atrophy are entities within the spectrum of atypical parkinsonism. The role of imaging methods in the diagnosis and differentiation between PSP and MSA is limited and Magnetic Resonance Imaging (MRI) is currently used as a reference modality. In this study, the authors examined a group of patients with atypical parkinsonism using a 1.5 T MRI system and aimed to find simple and repeatable measurements that may be useful to distinguish between these diseases. The results of the study indicate that the maximal width of the frontal horns of the lateral ventricles and Evans’ Index may, to some extent, be useful as basic and simple measurements in the diagnostic imaging of patients with atypical parkinsonism.

Publisher

MDPI AG

Subject

Clinical Biochemistry

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