Indigenous Medicinal Plants Used in the Management of Diabetes in Africa: 5 Years (2019–2024) in Perspective

Author:

Frimpong Ebenezer Kwabena1,Thembane Nokukhanya12,Hlatshwayo Sphamandla1,Ngcobo Mlungisi1,Gqaleni Nceba13

Affiliation:

1. Traditional Medicine Laboratory, School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban 4041, South Africa

2. Department of Biomedical Sciences, Faculty of Natural Science, Mangosuthu University of Technology, Durban 4026, South Africa

3. Africa Health Research Institute, 3rd Floor K-RITH Tower Building, Nelson R. Mandela School of Medicine, Durban 4001, South Africa

Abstract

(1) Background: The utilization of medicinal plants in the management of diabetes is of great importance to the health of the indigenous population on the African continent. The high cost of orthodox conventional medicines coupled with the perceived side effects encourages the high patronage of indigenous medicinal plants in the management of this metabolic disorder. We conducted a review on the indigenous African medicinal plants that could be useful in preclinical and clinical trials in the field of diabetes mellitus research. (2) Methods: Data were mined from research articles published and associated with the use of medicinal plants in the management of diabetes on the African continent (from January 2019 to March 2024). Literature from ethnobotanical studies on the African continent was searched from the Google Scholar, SCOPUS, Medline, Web of Science and PubMed databases. We employed the following keywords: “indigenous plants”, “diabetes in Africa” and “antidiabetic effect of medicinal plants”. (3) Results: A total of 52 medicinal plants belonging to 31 families were recorded in this study. Amaryllidaceae (14.28%), Fabaceae (9.52%) and Asteraceae (9.52%) were the most cited plant families. The frequently used indigenous medicinal plants on the African continent were Allium sativum L. (n = 6), Olea europaea L. (n = 6), Azadirachta indica A. Juss (n = 5), Allium cepa L. (n = 5) and Moringa oleifera Lam. (n = 5). The highly cited parts of the plant used in the management of diabetes were the leaves (45.55%), bark (14.44%) and bulbs (12.22%). The preferred methods of the preparation of herbal medicines were decoction (45.23%) and infusion (25%). Oral (52.32%) was the preferred route of the administration of herbal medicine on the African continent. (4) Conclusions: The data revealed some similarities in the way countries on the African continent manage diabetes. This interesting observation will assist in our quest towards obtaining a standardized protocol using indigenous medicinal plants to combat diseases on the African continent.

Funder

College of Health Sciences, University of KwaZulu-Natal

Publisher

MDPI AG

Reference112 articles.

1. International Diabetes Federation Diabetes (2019). Atlas, IDF. [9th ed.]. Available online: https://diabetesatlas.org/upload/resources/material/20200302_133351_IDFATLAS9e-final-web.pdf.

2. Global estimates of the prevalence of diabetes for 2010 and 2030;Shaw;Diabetes Res. Clin. Pract.,2010

3. Diabetes and diabetes medications;Turkoski;Orthop. Nurs.,2006

4. (2024, March 25). Available online: https://www.who.int/data/gho/indicator-metadata-registry/imr-details/2380#.

5. American Diabetes Association (2021). Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes—2021. Diabetes Care, 44, S15–S33.

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