A Fiber-Optical Dosimetry Sensor for Gamma-Ray Irradiation Measurement in Biological Applications

Author:

Elsharkawi Adel Shaaban Awad12ORCID,Alazab Huda A.3ORCID,Sayed Mahmoud1ORCID,Askar Mostafa A.4,Abdelrahman Ibrahim Y.4,Arafa Amany A.1ORCID,Saleh Hassan I.1,Gomaa Lotfy R.5ORCID,Du Yi-Chun67ORCID

Affiliation:

1. Department of Radiation Engineering, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo 11787, Egypt

2. Advanced Optoelectronic Technology Center, National Cheng Kung University, Tainan 70101, Taiwan

3. Nuclear and Radiological Safety Research Center, Egyptian Atomic Energy Authority, Cairo 9621, Egypt

4. Radiation Biology Department, National Center for Radiation Research and Technology (NCRRT), Egyptian Atomic Energy Authority (EAEA), Cairo 11787, Egypt

5. Faculty of Engineering at Shoubra, Banha University, Cairo 11672, Egypt

6. Department of Biomedical Engineering, National Cheng Kung University, Tainan 70101, Taiwan

7. Medical Device Innovation Center, National Cheng Kung University, Tainan 70101, Taiwan

Abstract

In this paper, we propose a novel fiber-optical dosimetry sensor for radiation measurement in biological applications. A two-dimensional (2D) fiber-optical dosimeter (FOD) for radiation measurement is considered. The sensors are arranged as a 2D array in a tailored holder. This FOD targets accurate industrial and medical applications which seek more tolerant radiation dosimeters. In this paper, the FOD sensors are subjected to gamma-ray radiation facilities from the 137Cs gamma-ray irradiator type for low doses and 60Co gamma-ray irradiator for high doses. For better evaluation of radiation effects on the FOD sample, the measurements are performed using eight sensors (hollow cylinder shape) with two samples in each dose. The sensors were measured before and after each irradiation. To the author’s knowledge, the measurements of FOD transplanted inside animals are presented for the first time in this paper. A 2D simulation program has been implemented for numerical simulation based on the attenuation factors from the absorbed dose inside the in vivo models. A comparison between the FOD and the standard thermo-luminescence detector is presented based on the test of in vivo animal models. The results indicate that the proposed FOD sensor is more stable and has higher sensitivity.

Funder

National Science and Technology Council

Publisher

MDPI AG

Subject

Clinical Biochemistry,General Medicine,Analytical Chemistry,Biotechnology,Instrumentation,Biomedical Engineering,Engineering (miscellaneous)

Reference51 articles.

1. Luminescence Dosimetry;Yukihara;Nat. Rev. Methods Prim.,2022

2. Thermoluminescence and Its Applications: A Review;Murthy;Defect Diffus. Forum,2014

3. Knoll, G.F. (2010). Radiation Detection and Measurement, John Wiley & Sons.

4. Kase, K. (2012). The Dosimetry of Ionizing Radiation, Elsevier.

5. Yasin, M., Harun, S.W., and Arof, H. (2012). Selected Topics on Optical Fiber Technology, IntechOpen.

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