Automatic Assessment of Transcatheter Aortic Valve Implantation Results on Four-Dimensional Computed Tomography Images Using Artificial Intelligence

Author:

Busto Laura1ORCID,Veiga César1ORCID,González-Nóvoa José A.1ORCID,Campanioni Silvia1ORCID,Juan-Salvadores Pablo1ORCID,Jiménez Díaz Víctor Alfonso2ORCID,Baz José Antonio2,Alba-Castro José Luis3ORCID,Kütting Maximilian4,Íñiguez Andrés2

Affiliation:

1. Cardiology Research Group, Galicia Sur Health Research Institute (IIS Galicia Sur), 36312 Vigo, Spain

2. Cardiology Department, Complexo Hospitalario Universitario de Vigo (SERGAS), Álvaro Cunqueiro Hospital, 36312 Vigo, Spain

3. atlanTTic Research Center for Telecommunication Technologies, University of Vigo, 36310 Vigo, Spain

4. New Valve Technology/Biosensors, 72379 Hechingen, Germany

Abstract

Transcatheter aortic valve implantation (TAVI) is a procedure to treat severe aortic stenosis. There are several clinical concerns related to potential complications after the procedure, which demand the analysis of computerized tomography (CT) scans after TAVI to assess the implant’s result. This work introduces a novel, fully automatic method for the analysis of post-TAVI 4D-CT scans to characterize the prosthesis and its relationship with the patient’s anatomy. The method enables measurement extraction, including prosthesis volume, center of mass, cross-sectional area (CSA) along the prosthesis axis, and CSA difference between the aortic root and prosthesis, all the variables studied throughout the cardiac cycle. The method has been implemented and evaluated with a cohort of 13 patients with five different prosthesis models, successfully extracting all the measurements from each patient in an automatic way. For Allegra patients, the mean of the obtained inner volume values ranged from 10,798.20 mm3 to 18,172.35 mm3, and CSA in the maximum diameter plane varied from 396.35 mm2 to 485.34 mm2. The implantation of this new method could provide information of the important clinical value that would contribute to the improvement of TAVI, significantly reducing the time and effort invested by clinicians in the image interpretation process.

Funder

Axencia Galega de Innovación

New Valve Technology (NVT) GmbH

Publisher

MDPI AG

Subject

Bioengineering

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