The Digital Twin: A Potential Solution for the Personalized Diagnosis and Treatment of Musculoskeletal System Diseases

Author:

Sun Tianze12ORCID,Wang Jinzuo12ORCID,Suo Moran12,Liu Xin12,Huang Huagui12ORCID,Zhang Jing12,Zhang Wentao12,Li Zhonghai12ORCID

Affiliation:

1. Department of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116600, China

2. Key Laboratory of Molecular Mechanism for Repair and Remodeling of Orthopedic Diseases, Dalian 116000, China

Abstract

Due to the high prevalence and rates of disability associated with musculoskeletal system diseases, more thorough research into diagnosis, pathogenesis, and treatments is required. One of the key contributors to the emergence of diseases of the musculoskeletal system is thought to be changes in the biomechanics of the human musculoskeletal system. However, there are some defects concerning personal analysis or dynamic responses in current biomechanical research methodologies. Digital twin (DT) was initially an engineering concept that reflected the mirror image of a physical entity. With the application of medical image analysis and artificial intelligence (AI), it entered our lives and showed its potential to be further applied in the medical field. Consequently, we believe that DT can take a step towards personalized healthcare by guiding the design of industrial personalized healthcare systems. In this perspective article, we discuss the limitations of traditional biomechanical methods and the initial exploration of DT in musculoskeletal system diseases. We provide a new opinion that DT could be an effective solution for musculoskeletal system diseases in the future, which will help us analyze the real-time biomechanical properties of the musculoskeletal system and achieve personalized medicine.

Funder

the Science and Technology Innovation Foundation of Dalian

the Natural Science Foundation of Liaoning Province

Publisher

MDPI AG

Subject

Bioengineering

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