The Influence of Vitamin D Levels on Dental Caries: A Retrospective Study of the United States Population

Author:

Hung Man1234ORCID,Patel Himani1,Lee Samantha1,Nguyen Justin1,Mohajeri Amir1ORCID

Affiliation:

1. College of Dental Medicine, Roseman University of Health Sciences, 10894 S. River Front Parkway, South Jordan, UT 84095, USA

2. Division of Public Health, University of Utah, Salt Lake City, UT 84108, USA

3. Department of Orthopaedic Surgery Operations, University of Utah, Salt Lake City, UT 84108, USA

4. George E. Wahlen Department, Veterans Affairs Medical Center, Salt Lake City, UT 84148, USA

Abstract

(1) Background: This study examines vitamin D’s impact on dental caries to inform prevention strategies, given its critical role in bone and calcium regulation, vital for dental health. (2) Methods: Data from 18,683 participants of the National Health and Nutrition Examination Survey (NHANES) 2011–2016 were analyzed. NHANES collects U.S. population data through interviews, physical exams, and tests, including vitamin D levels and dental health assessed using both the decayed, missing, and filled teeth (DMFT) index and the presence of untreated dental caries. Vitamin D levels were measured according to serum 25(OH)D concentrations, and the analyses adjusted for confounders such as body mass index (BMI) and socioeconomic status (SES) using Chi-square, Mann–Whitney U, Kruskal–Wallis tests, as well as logistic and Poisson regression. (3) Results: This study found a mean DMFT score of 7.36 and a 33.2% prevalence of untreated dental caries. A higher caries prevalence was correlated with a lower SES (p < 0.001), the male gender (p < 0.001), and a higher BMI (p < 0.001). Severe vitamin D deficiency (<25 nmol/L) doubled the risk of dental caries, with odds ratios of 2.261 and 1.953 after adjusting for demographic factors and BMI. (4) Conclusions: Our study confirms a significant relationship between low vitamin D levels and an increased risk of dental caries nationwide, even after accounting for sociodemographic factors, emphasizing the importance of maintaining sufficient vitamin D levels for preventing caries.

Publisher

MDPI AG

Reference57 articles.

1. Ross, A.C., Taylor, C.L., Yaktine, A.L., and Del Valle, H.B. (2011). DRI Dietary Reference Intakes Calcium Vitamin D, National Academies Press. Available online: https://nap.nationalacademies.org/read/13050/chapter/1.

2. Resurrection of vitamin D deficiency and rickets;Holick;J. Clin. Investig.,2006

3. Calcium and vitamin D: Skeletal and extraskeletal health;Khazai;Curr. Rheumatol. Rep.,2008

4. National Institute of Dental and Craniofacial Research (2024, April 18). Dental Caries (Tooth Decay), Available online: https://www.nidcr.nih.gov/research/data-statistics/dental-caries#.

5. Dental caries;Selwitz;Lancet,2007

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