Radiochemotherapy in Pancreatic Cancer

Author:

Domagała-Haduch Małgorzata1ORCID,Gorzelak-Magiera Anita1ORCID,Michalecki Łukasz1,Gisterek-Grocholska Iwona1ORCID

Affiliation:

1. Department of Oncology and Radiotherapy, Medical University of Silesia, 40-514 Katowice, Poland

Abstract

Despite the advancements made in oncology in recent years, the treatment of pancreatic cancer remains a challenge. Five-year survival rates for this cancer do not exceed 10%. Among the reasons contributing to poor treatment outcomes are the oligosymptomatic course of the tumor, diagnostic difficulties due to the anatomical location of the organ, and the unique biological features of pancreatic cancer. The mainstay of treatment for resectable cancer is surgery and adjuvant chemotherapy. For unresectable and metastatic cancers, chemotherapy remains the primary method of treatment. At the same time, for about thirty years, there have been attempts to improve treatment outcomes by using radiotherapy combined with systemic treatment. Unlike chemotherapy, radiotherapy has no established place in the treatment of pancreatic cancer. This paper addresses the topic of radiotherapy in pancreatic cancer as a valuable method that can improve treatment outcomes alongside chemotherapy.

Funder

Medical University of Silesia, Katowice, Poland

Publisher

MDPI AG

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