Affiliation:
1. Department of Cardiology, Lanzhou University Second Hospital, Lanzhou 730031, China
2. Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou 730031, China
Abstract
With increasing research, the sirtuin (SIRT) protein family has become increasingly understood. Studies have demonstrated that SIRTs can aid in metabolism and affect various physiological processes, such as atherosclerosis, heart failure (HF), hypertension, type 2 diabetes, and other related disorders. Although the pathogenesis of HF with preserved ejection fraction (HFpEF) has not yet been clarified, SIRTs have a role in its development. Therefore, SIRTs may offer a fresh approach to the diagnosis, treatment, and prevention of HFpEF as a novel therapeutic intervention target.
Funder
National Natural Science Foundation of China
Gansu science and Technology Department Project
Cuiying Scientific and Technological Innovation Program of Lanzhou University Second Hospital
Gansu heart rehabilitation engineering research center
Lanzhou University Medical Postgraduate Training Innovation Development Project
Provincial Talent Project in 2024
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