Implantable Pressure-Sensing Devices for Monitoring Abdominal Aortic Aneurysms in Post-Endovascular Aneurysm Repair

Author:

Silva Nuno P.12ORCID,Amin Bilal123ORCID,Dunne Eoghan123ORCID,Hynes Niamh4ORCID,O’Halloran Martin123ORCID,Elahi Adnan12ORCID

Affiliation:

1. Translational Medical Device Lab, University of Galway, H91 TK33 Galway, Ireland

2. Electrical and Electronic Engineering, University of Galway, H91 TK33 Galway, Ireland

3. School of Medicine, University of Galway, H91 TK33 Galway, Ireland

4. Western Vascular Institute, Galway Clinic, Doughiska Road, H91 HHT0 Galway, Ireland

Abstract

Over the past two decades, there has been extensive research into surveillance methods for the post-endovascular repair of abdominal aortic aneurysms, highlighting the importance of these technologies in supplementing or even replacing conventional image-screening modalities. This review aims to provide an overview of the current status of alternative surveillance solutions for endovascular aneurysm repair, while also identifying potential aneurysm features that could be used to develop novel monitoring technologies. It offers a comprehensive review of these recent clinical advances, comparing new and standard clinical practices. After introducing the clinical understanding of abdominal aortic aneurysms and exploring current treatment procedures, the paper discusses the current surveillance methods for endovascular repair, contrasting them with recent pressure-sensing technologies. The literature on three commercial pressure-sensing devices for post-endovascular repair surveillance is analyzed. Various pre-clinical and clinical studies assessing the safety and efficacy of these devices are reviewed, providing a comparative summary of their outcomes. The review of the results from pre-clinical and clinical studies suggests a consistent trend of decreased blood pressure in the excluded aneurysm sac post-repair. However, despite successful pressure readings from the aneurysm sac, no strong link has been established to translate these measurements into the presence or absence of endoleaks. Furthermore, the results do not allow for a conclusive determination of ongoing aneurysm sac growth. Consequently, a strong clinical need persists for monitoring endoleaks and aneurysm growth following endovascular repair.

Funder

Science Foundation Ireland

Publisher

MDPI AG

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