Effects of a Specialized Oral Nutritional Supplement with Dietary Counseling on Nutritional Outcomes in Community-Dwelling Older Adults at Risk of Malnutrition: A Randomized Controlled Trial-Reference-Cited by-同舟云学术

Effects of a Specialized Oral Nutritional Supplement with Dietary Counseling on Nutritional Outcomes in Community-Dwelling Older Adults at Risk of Malnutrition: A Randomized Controlled Trial

Published:2024-08-17 Issue:4 Volume:9 Page:104
ISSN:2308-3417
Container-title:Geriatrics
language:en
Short-container-title:Geriatrics

Author:

Muangpaisan Weerasak¹^ORCID,Wichansawakun Sanit²^ORCID,Huynh Dieu Thi Thu³,Intalapaporn Somboon¹,Chalermsri Chalobol¹,Thititagul Ornicha¹,Chupisanyarote Kanokkarn⁴,Chuansangeam Mallika²,Laiteerapong Arunee⁵,Yalawar Menaka⁶^ORCID,Huang Chengrong⁷,Tey Siew Ling³^ORCID,Liu Zhongyuan³

Affiliation:

1. Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand

2. Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand

3. Abbott Nutrition Research and Development, Asia-Pacific Center, Singapore 138668, Singapore

4. Thammasat University Hospital, Thammasat University, Pathum Thani 12120, Thailand

5. Abbott Nutrition Research and Development, Bangkok 10120, Thailand

6. Biostatistics and Statistical Programming, Cognizant Technologies Solution Pvt. Ltd., Bangalore 560092, India

7. Abbott Nutrition Research and Development, Shanghai 200233, China

Abstract

This study investigated the effects of oral nutritional supplements (ONSs) along with dietary counseling (DC) in community-dwelling older adults at risk of malnutrition. In this randomized controlled trial, 196 older adults who were at risk of malnutrition, as identified by the Malnutrition Universal Screening Tool (MUST) were randomly assigned to receive ONSs twice daily with DC (intervention) or DC-only (control) for 60 days. Primary outcome was change in body weight from baseline to day 60. Nutritional status, energy, and macronutrient intakes were measured. A significant larger weight gain was observed in the intervention compared to the control from baseline to day 60 (1.50 ± 0.22 kg, p < 0.0001). The intervention group also showed a significantly greater increase in weight at day 30 (p < 0.0001). Intakes of energy and macronutrients were significantly higher in the intervention group compared to the control group at both days 30 and 60 (all p < 0.0001). The odds of achieving better nutritional status were significantly higher in the intervention group than in the control group (OR:3.9, 95% CI: 1.9, 8.2, p = 0.0001). ONS supplementation combined with DC significantly improved body weight and nutritional outcomes in community-dwelling older adults at risk of malnutrition.

Funder

Abbott Nutrition

Publisher

MDPI AG

Link

https://www.mdpi.com/2308-3417/9/4/104/pdf

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