hiPSC-Derived Cells as Models for Drug Discovery 2.0-Reference-Cited by-同舟云学术

hiPSC-Derived Cells as Models for Drug Discovery 2.0

Published:2023-03-17 Issue:6 Volume:24 Page:5727
ISSN:1422-0067
Container-title:International Journal of Molecular Sciences
language:en
Short-container-title:IJMS

Author:

Ofir Rivka¹²^ORCID

Affiliation:

1. The Regenerative Medicine and Stem Cell (RMSC) Research Center, Ben-Gurion University of the Negev, Beer Sheva 84105, Israel

2. Dead Sea & Arava Science Center, Masada 8691000, Israel

Abstract

Human-induced pluripotent stem cells (hiPSCs) serve as a sustainable resource for studying the molecular foundation of disease development, including initiation and deterioration [...]

Funder

The Ministry of Innovation Science and Technology

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

Link

https://www.mdpi.com/1422-0067/24/6/5727/pdf

Reference18 articles.

1. Costa, A.D.S., Mortensen, P., Hortigon-Vinagre, M.P., van der Heyden, M.A.G., Burton, F.L., Gao, H., Simitev, R.D., and Smith, G.L. (2021). Electrophysiology of hiPSC-Cardiomyocytes Co-Cultured with HEK Cells Expressing the Inward Rectifier Channel. Int. J. Mol. Sci., 22.

2. Álvarez, M., Ruiz-Sala, P., Pérez, B., Desviat, L.R., and Richard, E. (2023). Dysregulated Cell Homeostasis and miRNAs in Human iPSC-Derived Cardiomyocytes from a Propionic Acidemia Patient with Cardiomyopathy. Int. J. Mol. Sci., 24.

3. Ben-Zvi, H., Rabinski, T., Ofir, R., Cohen, S., and Vatine, G.D. (2022). PLEKHM2 Loss of Function Impairs the Activity of iPSC-Derived Neurons via Regulation of Autophagic Flux. Int. J. Mol. Sci., 23.

4. PLEKHM2 mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction;Muhammad;Hum. Mol. Genet.,2015

5. Walker, L.M., Sparks, N.R.L., Puig-Sanvicens, V., Rodrigues, B., and zur Nieden, N.I. (2021). An Evaluation of Human Induced Pluripotent Stem Cells to Test for Cardiac Developmental Toxicity. Int. J. Mol. Sci., 22.