Metabolomics Approaches for the Diagnosis, Treatment, and Better Disease Management of Viral Infections

Author:

Al-Sulaiti Haya12,Almaliti Jehad34,Naman C. Benjamin5ORCID,Al Thani Asmaa A.126,Yassine Hadi M.26ORCID

Affiliation:

1. QU Health, Qatar University, Doha P.O. Box 2713, Qatar

2. Biomedical Research Center, Qatar University, Doha P.O. Box 2713, Qatar

3. Scripps Institution of Oceanography, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA P.O. Box 92093, USA

4. Department of Pharmaceutical Sciences, College of Pharmacy, The University of Jordan, Amman P.O. Box 11942, Jordan

5. Department of Science and Conservation, San Diego Botanic Garden, Encinitas, CA P.O. Box 92024, USA

6. College of Health Sciences, QU-Health, Qatar University, Doha P.O. Box 2713, Qatar

Abstract

Metabolomics is an analytical approach that involves profiling and comparing the metabolites present in biological samples. This scoping review article offers an overview of current metabolomics approaches and their utilization in evaluating metabolic changes in biological fluids that occur in response to viral infections. Here, we provide an overview of metabolomics methods including high-throughput analytical chemistry and multivariate data analysis to identify the specific metabolites associated with viral infections. This review also focuses on data interpretation and applications designed to improve our understanding of the pathogenesis of these viral diseases.

Funder

Qatar National Research Fund

Publisher

MDPI AG

Subject

Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

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