The Impact of Tannic Acid Consumption on Bone Mineralization

Author:

Winiarska-Mieczan Anna1ORCID,Muszyński Siemowit2ORCID,Tomaszewska Ewa3ORCID,Kwiecień Małgorzata4ORCID,Donaldson Janine5ORCID,Tomczyk-Warunek Agnieszka6,Blicharski Tomasz7ORCID

Affiliation:

1. Department of Bromatology and Food Physiology, Institute of Animal Nutrition and Bromatology, University of Life Sciences in Lublin, 20-950 Lublin, Poland

2. Department of Biophysics, University of Life Sciences in Lublin, 20-950 Lublin, Poland

3. Department of Animal Physiology, University of Life Sciences in Lublin, 20-950 Lublin, Poland

4. Department of Animal Nutrition, Institute of Animal Nutrition and Bromatology, University of Life Sciences in Lublin, 20-950 Lublin, Poland

5. School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Parktown, Johannesburg 2193, South Africa

6. Laboratory of Locomotor System Research, Department of Rehabilitation and Physiotherapy, Medical University in Lublin, 20-090 Lublin, Poland

7. Department of Orthopaedics and Rehabilitation, Medical University in Lublin, 20-090 Lublin, Poland

Abstract

Tannic acid (TA) is an organic compound belonging to the tannin group. Like other tannins, it has an affinity for endogenous proteins, including digestive enzymes, which can result in the reduced digestibility and absorption of nutrients. It can also form complexes with mineral components, reducing their absorption. In some cases, this can be beneficial, such as in the case of toxic metals, but sometimes it may have a detrimental effect on the body when it involves essential mineral components like Ca, P, Mg, Na, K, or Fe. Therefore, the impact of TA on bone health should be considered from both perspectives. This relatively short review summarizes the available information and research findings on TA, with a particular focus on its potential impact on bone health. It is worth noting that future research and clinical studies may provide more detailed and precise information on this topic, allowing for a better understanding of the role of TA in maintaining the integrity of the musculoskeletal system. Despite its brevity, this paper represents a valuable contribution to the analysis of the potential benefits and challenges associated with TA in the context of bone health. We anticipate that future research will continue along this important research line, expanding our knowledge of the influence of this compound on the skeletal system and its potential therapeutic applications.

Publisher

MDPI AG

Subject

Molecular Biology,Biochemistry,Endocrinology, Diabetes and Metabolism

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