A Bioactive Enamel Sealer Can Protect Enamel during Orthodontic Treatment: An In Vitro Study

Abstract

Background: This study aimed to evaluate the effectiveness of an experimental bioactive enamel resin sealer in protecting the enamel adjacent to orthodontic brackets against erosion. Methods: Orthodontic brackets (n = 50) were bonded to freshly extracted, sound maxillary premolars using Transbond™ XT Primer (3M Unitek, Monrovia, CA, USA) and Transbond Plus Color Change adhesive (3M Unitek, USA). Five experimental groups (n = 10) had the following treatments applied: a resin bioactive sealer with 45S5 bioglass, 35% by weight; a resin sealer without bioactive glass; fluoride; the orthodontic sealer, Opal Seal (Opal-Orthodontics, South Jordan, UT, USA); and, in the control group, an untreated surface. All the specimens were stored for 18 min in 1% citric acid. All the specimens were examined by SEM and electron dispersive spectroscopy (EDS). The Wilcoxon signed-rank test was used to compare the enamel surfaces covered by the sealers before and after the acid challenge. Attenuated total reflectance Fourier transform infrared spectroscopy detected the degree of the experimental resins’ conversion to verify their suitability for clinical use. Results: The percentage of the bioactive resin sealer and Opal Seal groups’ protection against enamel erosion was 100%, which was significantly more than the other groups, p < 0.05. The degree of conversion for the bioactive and unfilled resins was 42.4% ± 3.6% and 48.57% ± 5%, respectively. Conclusion: The bioactive resin sealer and the Opal Seal both protected the enamel from erosion.