Development of Vitamin C-Loaded Electrospun Nanofibers of Mixture of Polysaccharides of Pullulan/Xanthan Gum for Fast Dissolving Oral Film Applications-Reference-Cited by-同舟云学术

Development of Vitamin C-Loaded Electrospun Nanofibers of Mixture of Polysaccharides of Pullulan/Xanthan Gum for Fast Dissolving Oral Film Applications

Published:2024-02-12 Issue:4 Volume:17 Page:861
ISSN:1996-1944
Container-title:Materials
language:en
Short-container-title:Materials

Author:

Cheng En¹,Geng Zhanhui²,Xiang Lubing¹,Zhao Xiaoying¹,Xiang Aimin¹,Tian Huafeng¹

Affiliation:

1. School of Light Industry Science and Engineering, Beijing Technology and Business University, Beijing 100048, China

2. Systems Engineering Institute, Academy of Military Science, People’s Liberation Army, Beijing 100010, China

Abstract

In this study, polysaccharide-based nanofibrous fast dissolving oral films (FDOFs) were developed using pullulan (PUL) and xanthan gum (XG) via electrospinning. The edible, continuous, and bead-free nanofibers with average diameters ranging from 181.17 nm to 260.84 nm were prepared. The morphological, thermal, mechanical, and water-soluble properties of the nanofibrous FDOFs were characterized. For prospective future applications of the developed PUL/XG FDOFs, a model nutrient of vitamin C (VC) was encapsulated into the FDOFs. The success of VC encapsulation was confirmed by Fourier transform infrared spectroscopy. The encapsulation efficiency of VC was above 85% by ultraviolet-visible spectrophotometer. The amorphous structure of PUL/XG in the nanofibers film was demonstrated by X-ray diffractometer. In addition, the edible FDOFs could dissolve in water within 3 s. The nanofibers film we prepared could be used as nutrient or drug carriers and edible packaging film.

Publisher

MDPI AG

Link

https://www.mdpi.com/1996-1944/17/4/861/pdf

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