Affiliation:
1. School of Engineering, The University of Edinburgh, Edinburgh EH9 3FF, UK
Abstract
Neurodegenerative diseases (NDs) can be life threatening and have chronic impacts on patients and society. Timely diagnosis and treatment are imperative to prevent deterioration. Conventional imaging modalities, such as Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and Positron Emission Tomography (PET), are expensive and not readily accessible to patients. Microwave sensing and imaging (MSI) systems are promising tools for monitoring pathological changes, namely the lateral ventricle enlargement associated with ND, in a non-invasive and convenient way. This paper presents a dual-planar monopole antenna-based remote sensing system for ND monitoring. First, planar monopole antennas were designed using the simulation software CST Studio Suite. The antenna analysis was carried out regarding the reflection coefficient, gain, radiation pattern, time domain characterization, E-field distribution, and Specific Absorption Rate (SAR). The designed antennas were then integrated with a controlling circuit as a remote sensing system. The system was experimentally validated on brain phantoms using a vector network analyzer and a laptop. The collected reflection coefficient data were processed using a radar-based imaging algorithm to reconstruct images indicating brain abnormality in ND. The results suggest that the system could serve as a low-cost and efficient tool for long-term monitoring of ND, particularly in clinics and care home scenarios.