Abstract
Collagen type I (Col-I) is unique due to its high biocompatibility in human tissue. Despite its availability from various sources, Col-I naturally mimics the extracellular matrix (ECM) and generally makes up the larger protein component (90%) in vasculature, skin, tendon bone, and other tissue. The acceptable physicochemical properties of native Col-I further enhance the incorporation of Col-I in various fields, including pharmaceutical, cosmeceutical, regenerative medicine, and clinical. This review aims to discuss Col-I, covering the structure, various sources of availability, native collagen synthesis, current extraction methods, physicochemical characteristics, applications in various fields, and biomarkers. The review is intended to provide specific information on Col-I currently available, going back five years. This is expected to provide a helping hand for researchers who are concerned about any development on collagen-based products particularly for therapeutic fields.
Subject
Polymers and Plastics,General Chemistry
Reference122 articles.
1. Collagen fibril assembly and function;Holmes,2018
2. Anatomy of the fascia from the clinical point of view;Luomala,2016
3. Collagen type I: A versatile biomaterial;Chowdhury,2018
4. Collagen/chitosan composite scaffolds for bone and cartilage tissue engineering;Chicatun,2017
5. Structure and function;Petty,2016
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