Recent Trends and Innovations in Bead-Based Biosensors for Cancer Detection-Reference-Cited by-同舟云学术

Recent Trends and Innovations in Bead-Based Biosensors for Cancer Detection

Published:2024-05-01 Issue:9 Volume:24 Page:2904
ISSN:1424-8220
Container-title:Sensors
language:en
Short-container-title:Sensors

Author:

Cheng Hui-Pin¹,Yang Tai-Hua¹²³^ORCID,Wang Jhih-Cheng⁴⁵⁶,Chuang Han-Sheng¹³^ORCID

Affiliation:

1. Department of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan

2. Department of Orthopedic Surgery, National Cheng Kung University Hospital, Tainan 704, Taiwan

3. Medical Device Innovation Center, National Cheng Kung University, Tainan 701, Taiwan

4. Department of Urology, Chimei Medical Center, Tainan 710, Taiwan

5. Department of Electrical Engineering, Southern Taiwan University of Science and Technology, Tainan 710, Taiwan

6. School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung 804, Taiwan

Abstract

Demand is strong for sensitive, reliable, and cost-effective diagnostic tools for cancer detection. Accordingly, bead-based biosensors have emerged in recent years as promising diagnostic platforms based on wide-ranging cancer biomarkers owing to the versatility, high sensitivity, and flexibility to perform the multiplexing of beads. This comprehensive review highlights recent trends and innovations in the development of bead-based biosensors for cancer-biomarker detection. We introduce various types of bead-based biosensors such as optical, electrochemical, and magnetic biosensors, along with their respective advantages and limitations. Moreover, the review summarizes the latest advancements, including fabrication techniques, signal-amplification strategies, and integration with microfluidics and nanotechnology. Additionally, the challenges and future perspectives in the field of bead-based biosensors for cancer-biomarker detection are discussed. Understanding these innovations in bead-based biosensors can greatly contribute to improvements in cancer diagnostics, thereby facilitating early detection and personalized treatments.

Funder

Ministry of Science and Technology,Taiwan

Publisher

MDPI AG

Link

https://www.mdpi.com/1424-8220/24/9/2904/pdf

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