Machine Learning-Assisted 3D Flexible Organic Transistor for High-Accuracy Metabolites Analysis and Other Clinical Applications

Author:

Liao Caizhi12,Wu Huaxing2,Occhipinti Luigi G.1ORCID

Affiliation:

1. Department of Engineering, The University of Cambridge, Cambridge CB2 1TN, UK

2. Department of Bioengineering, Sun Yat-Sen University, Guangzhou 510275, China

Abstract

The integration of advanced diagnostic technologies in healthcare is crucial for enhancing the accuracy and efficiency of disease detection and management. This paper presents an innovative approach combining machine learning-assisted 3D flexible fiber-based organic transistor (FOT) sensors for high-accuracy metabolite analysis and potential diagnostic applications. Machine learning algorithms further enhance the analytical capabilities of FOT sensors by effectively processing complex data, identifying patterns, and predicting diagnostic outcomes with 100% high accuracy. We explore the fabrication and operational mechanisms of these transistors, the role of machine learning in metabolite analysis, and their potential clinical applications by analyzing practical human blood samples for hypernatremia syndrome. This synergy not only improves diagnostic precision but also holds potential for the development of personalized diagnostics, tailoring treatments for individual metabolic profiles.

Funder

Ministry of Industry and Information Technology

EPSRC

Publisher

MDPI AG

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