Computer-Aided Detection of Fiducial Points in Seismocardiography through Dynamic Time Warping

Author:

Chen Chien-HungORCID,Lin Wen-YenORCID,Lee Ming-YihORCID

Abstract

Accelerometer-based devices have been employed in seismocardiography fiducial point detection with the aid of quasi-synchronous alignment between echocardiography images and seismocardiogram signals. However, signal misalignments have been observed, due to the heartbeat cycle length variation. This paper not only analyzes the misalignments and detection errors but also proposes to mitigate the issues by introducing reference signals and adynamic time warping (DTW) algorithm. Two diagnostic parameters, the ratio of pre-ejection period to left ventricular ejection time (PEP/LVET) and the Tei index, were examined with two statistical verification approaches: (1) the coefficient of determination (R2) of the parameters versus the left ventricular ejection fraction (LVEF) assessments, and (2) the receiver operating characteristic (ROC) classification to distinguish the heart failure patients with reduced ejection fraction (HFrEF). Favorable R2 values were obtained, R2 = 0.768 for PEP/LVET versus LVEF and R2 = 0.86 for Tei index versus LVEF. The areas under the ROC curve indicate the parameters that are good predictors to identify HFrEF patients, with an accuracy of more than 92%. The proof-of-concept experiments exhibited the effectiveness of the DTW-based quasi-synchronous alignment in seismocardiography fiducial point detection. The proposed approach may enable the standardization of the fiducial point detection and the signal template generation. Meanwhile, the program-generated annotation data may serve as the labeled training set for the supervised machine learning.

Funder

Ministry of Science and Technology, Taiwan

Chang Gung University, Taiwan

Publisher

MDPI AG

Subject

Clinical Biochemistry,General Medicine

Reference39 articles.

1. Systolic Time Intervals and New Measurement Methods

2. A critical review of the systolic time intervals.

3. Respiratory modulation of cardiac time intervals.

4. New index of combined systolic and diastolic myocardial performance: A simple and reproducible measure of cardiac function—A study in normals and dilated cardiomyopathy;Chuwa;J. Cardiol.,1995

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